8KDC
| Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in monomeric form | 分子名称: | MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... | 著者 | Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. | 登録日 | 2023-08-09 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
|
|
8KDB
| Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in dimeric form | 分子名称: | MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... | 著者 | Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. | 登録日 | 2023-08-09 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
|
|
5YXC
| Crystal structure of Zinc binding protein ZinT in complex with citrate from E. coli | 分子名称: | CITRIC ACID, Metal-binding protein ZinT, ZINC ION | 著者 | Chen, J, Wang, L, Shang, F, Xu, Y. | 登録日 | 2017-12-04 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.763 Å) | 主引用文献 | Crystal structure of E. coli ZinT with one zinc-binding mode and complexed with citrate Biochem. Biophys. Res. Commun., 500, 2018
|
|
5Z7H
| |
1NI1
| Imidazole and cyanophenyl farnesyl transferase inhibitors | 分子名称: | 2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... | 著者 | Tong, Y, Lin, N.H, Wang, L, Hasvold, L, Wang, W, Leonard, N, Li, T, Li, Q, Cohen, J, Gu, W.Z, Zhang, H, Stoll, V, Bauch, J, Marsh, K, Rosenberg, S.H, Sham, H.L. | 登録日 | 2002-12-20 | 公開日 | 2004-04-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability. Bioorg.Med.Chem.Lett., 13, 2003
|
|
9AYF
| Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-07 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 2024
|
|
9AVL
| Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-04 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 2024
|
|
9AVG
| Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-02 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 2024
|
|
9AXF
| Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-06 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 2024
|
|
9ASB
| Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-02-24 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 2024
|
|
8K4Y
| Structure of a triple-helix region of human ReCol 3 from Trautec | 分子名称: | SULFATE ION, triple-helix region of human ReCol 3 | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a triple-helix region of human ReCol 3 from Trautec. To Be Published
|
|
8K4X
| Structure of a triple-helix region of human Collagen type XVII from Trautec | 分子名称: | triple-helix region of human Collagen type XVII | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of a triple-helix region of human Collagen type XVII from Trautec. To Be Published
|
|
8K4W
| Structure of a triple-helix region of human collagen type I from Trautec | 分子名称: | CHLORIDE ION, triple-helix region of human collagen type I | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a triple-helix region of human collagen type I from Trautec. To Be Published
|
|
8K9G
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-08-01 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
|
|
1YD0
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: manganese | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD3
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y43F bound to its catalytic divalent cation | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD1
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium | 分子名称: | GLYCEROL, MAGNESIUM ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD5
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant N88A bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD4
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y29F bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YCZ
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima | 分子名称: | GLYCEROL, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD6
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Bacillus caldotenax | 分子名称: | CHLORIDE ION, SULFATE ION, UvrC | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
1YD2
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y19F bound to the catalytic divalent cation | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
|
|
4WUM
| |
4YFF
| TNNI3K complexed with inhibitor 2 | 分子名称: | 3-[(5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-N-methyl-4-(morpholin-4-yl)benzenesulfonamide, Serine/threonine-protein kinase TNNI3K | 著者 | Shewchuk, L.M, Wang, L, Lawhorn, B.G. | 登録日 | 2015-02-25 | 公開日 | 2015-09-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K). J.Med.Chem., 58, 2015
|
|
3TKR
| Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | 分子名称: | Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
|
|