8PFJ
 
 | | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-16 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PH9
 | | E. coli RNA polymerase paused at ops site (non-complementary scaffold) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-19 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PID
 | | backtracked E. coli transcription complex paused at ops site and bound to RfaH | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-21 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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7PX3
 | | Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | | Descriptor: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-10-07 | | Release date: | 2022-01-26 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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5NX0
 | | Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at room temperature | | Descriptor: | Endolysin | | Authors: | Gohlke, U, Loll, B, Consentius, P, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | | Deposit date: | 2017-05-09 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.803 Å) | | Cite: | Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Phys Chem Chem Phys, 19, 2017
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8PFG
 | | autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex), not fully complementary scaffold | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-15 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PHK
 | | fully recruited RfaH bound to E. coli transcription complex paused at ops site | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-20 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PIB
 | | autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-21 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PIL
 | | E. coli transcription complex paused at ops site and bound to RfaH and NusA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-22 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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8PIM
 | | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold) | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | | Deposit date: | 2023-06-22 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
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7AKP
 | | Crystal structure of E. coli RNA helicase HrpA-D305A | | Descriptor: | ATP-dependent RNA helicase HrpA | | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-10-01 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7B3A
 | | Crystal structure of PamZ | | Descriptor: | ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ... | | Authors: | Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C. | | Deposit date: | 2020-11-30 | | Release date: | 2021-11-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Molecular basis of antibiotic self-resistance in a bee larvae pathogen.
Nat Commun, 13, 2022
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7BDK
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ... | | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | Deposit date: | 2020-12-21 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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7BDJ
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS | | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | Deposit date: | 2020-12-21 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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7BDL
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ADP | | Descriptor: | MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | Deposit date: | 2020-12-21 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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7BDI
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ATPgammaS | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pre-mRNA-processing-splicing factor 8, ... | | Authors: | Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. | | Deposit date: | 2020-12-21 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
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8Q3Q
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8Q3N
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8Q3O
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8Q3P
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7OS2
 | | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | | Descriptor: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-06-07 | | Release date: | 2022-02-23 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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7OS1
 | | Cryo-EM structure of Brr2 in complex with Fbp21 | | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-06-07 | | Release date: | 2022-02-23 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
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8PTP
 | | Structure of Rho pentamer in complex with Rof | | Descriptor: | Protein rof, Transcription termination factor Rho | | Authors: | Said, N, Hilal, T, Wahl, M.C. | | Deposit date: | 2023-07-14 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
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8PTN
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8PTM
 | | Structure of the transcription termination factor Rho in complex with Rof and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein rof, ... | | Authors: | Said, N, Hilal, T, Wahl, M.C. | | Deposit date: | 2023-07-14 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation.
Nat Commun, 15, 2024
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