6EC6
| Ruminococcus gnavus Beta-glucuronidase | Descriptor: | Beta-glucuronidase, CHLORIDE ION, GLYCEROL | Authors: | Biernat, K.A, Redinbo, M.R. | Deposit date: | 2018-08-07 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
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3ET7
| Crystal structure of PYK2 complexed with PF-2318841 | Descriptor: | 5-{[4-{[2-(pyrrolidin-1-ylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,3-dihydro-2H-indol-2-one, PHOSPHATE ION, Protein tyrosine kinase 2 beta | Authors: | Han, S. | Deposit date: | 2008-10-07 | Release date: | 2009-06-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation. Bioorg.Med.Chem.Lett., 18, 2008
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3FOC
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3FU1
| Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio cholerae | Descriptor: | CALCIUM ION, General secretion pathway protein G, ZINC ION | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | Deposit date: | 2009-01-13 | Release date: | 2009-07-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system. J.Biol.Chem., 284, 2009
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3G20
| Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | Deposit date: | 2009-01-30 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system. J.Biol.Chem., 284, 2009
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1TII
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3GN9
| Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio vulnificus | Descriptor: | CALCIUM ION, D-MALATE, Type II secretory pathway, ... | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | Deposit date: | 2009-03-16 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system. J.Biol.Chem., 284, 2009
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3HZR
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3I05
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3HV0
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3HRK
| Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidyl-adenylate complex) | Descriptor: | CHLORIDE ION, HISTIDYL-ADENOSINE MONOPHOSPHATE, Histidyl-tRNA synthetase | Authors: | Arakaki, T.L, Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2009-06-09 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs. J.Mol.Biol., 397, 2010
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3HRI
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2B4T
| Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 Angstrom resolution reveals intriguing extra electron density in the active site | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase | Authors: | Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | Deposit date: | 2005-09-26 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site Proteins, 62, 2006
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2B9S
| Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', 5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ... | Authors: | Davies, D.R, Hol, W.G.J. | Deposit date: | 2005-10-12 | Release date: | 2006-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA. J.Mol.Biol., 357, 2006
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2B4G
| dihydroorotate dehydrogenase | Descriptor: | BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | Deposit date: | 2005-09-23 | Release date: | 2005-10-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies Mol.Microbiol., 68, 2008
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3P0I
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3P0H
| Leishmania major Tyrosyl-tRNA synthetase in complex with fisetin, cubic crystal form | Descriptor: | 3,7,3',4'-TETRAHYDROXYFLAVONE, Tyrosyl-tRNA synthetase | Authors: | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2010-09-28 | Release date: | 2011-03-23 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer. J.Mol.Biol., 409, 2011
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2C4R
| Catalytic domain of E. coli RNase E | Descriptor: | MAGNESIUM ION, RIBONUCLEASE E, SSRNA MOLECULE: 5'-R(*AP*CP*AP*GP*UP*AP*UP*UP*UP*GP)-3', ... | Authors: | Marcaida, M.J, Callaghan, A.J, Luisi, B.F. | Deposit date: | 2005-10-21 | Release date: | 2005-10-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover Nature, 437, 2005
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3P0J
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3OSS
| The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system | Descriptor: | CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ... | Authors: | Korotkov, K.V, Pruneda, J, Hol, W.G.J. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural and functional studies on the interaction of GspC and GspD in the type II secretion system. Plos Pathog., 7, 2011
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2EPH
| Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.7 angstrom resolution | Descriptor: | Fructose-bisphosphate aldolase, PbTRAP | Authors: | Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | Deposit date: | 2007-03-30 | Release date: | 2007-04-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2F8M
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3S84
| Dimeric apoA-IV | Descriptor: | Apolipoprotein A-IV, SULFATE ION | Authors: | Deng, X, Davidson, W.S, Thompson, T.B. | Deposit date: | 2011-05-27 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association. Structure, 20, 2012
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3SX9
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3SOL
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