2C4R

Catalytic domain of E. coli RNase E

Summary for 2C4R

Related1SLJ 1SMX 1SN8 2BX2 2C0B
DescriptorRIBONUCLEASE E, SSRNA MOLECULE: 5'-R(*AP*CP*AP*GP*UP*AP*UP*UP*UP*GP)-3', MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsrna binding, rna turnover, rna processing, hydrolase, endonuclease, nuclease
Biological sourceESCHERICHIA COLI
Cellular locationCytoplasm  P21513
Total number of polymer chains2
Total molecular weight61492.07
Authors
Marcaida, M.J.,Callaghan, A.J.,Luisi, B.F. (deposition date: 2005-10-21, release date: 2005-10-25, Last modification date: 2018-04-04)
Primary citation
Callaghan, A.J.,Marcaida, M.J.,Stead, J.A.,McDowall, K.J.,Scott, W.G.,Luisi, B.F.
Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Nature, 437:1187-, 2005
PubMed: 16237448 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE04084
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.6 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRNA backbone0.2679614.1%35.0%0.03MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2c4r
no rotation
Molmil generated image of 2c4r
rotated about x axis by 90°
Molmil generated image of 2c4r
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2c4r
no rotation
Molmil generated image of 2c4r
rotated about x axis by 90°
Molmil generated image of 2c4r
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2c4r.pdb1.gz [298.75 KB])