3P0J

Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, triclinic crystal form 1

Summary for 3P0J

• Entry DOI: 10.2210/pdb3p0j/pdb
• Related: 3P0H 3P0I
• Descriptor: Tyrosyl-tRNA synthetase, 4-[(2S)-2-amino-3-hydroxypropyl]phenol, SODIUM ION (3 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, trna ligase, aars, tyrrs, pseudodimer, translation, atp-binding, nucleotide-binding, ligase, structural genomics, medical structural genomics of pathogenic protozoa, msgpp
• Biological source: Leishmania major
• Total number of polymer chains: 4
• Total formula weight: 305004.33

Authors

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2010-09-28, release date: 2011-03-23, Last modification date: 2023-12-06)

• Primary citation: Larson, E.T.,Kim, J.E.,Castaneda, L.J.,Napuli, A.J.,Zhang, Z.,Fan, E.,Zucker, F.H.,Verlinde, C.L.,Buckner, F.S.,Van Voorhis, W.C.,Hol, W.G.,Merritt, E.A.; The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.; J.Mol.Biol., 409:159-176, 2011; PubMed: 21420975; DOI: 10.1016/j.jmb.2011.03.026

Experimental method

X-RAY DIFFRACTION (2.89 Å)