7YRY
| F1-ATPase of Acinetobacter baumannii | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Saw, W.-G, Grueber, G. | Deposit date: | 2022-08-11 | Release date: | 2023-06-21 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Atomic insights of an up and down conformation of the Acinetobacter baumannii F 1 -ATPase subunit epsilon and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis. Faseb J., 37, 2023
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7Y5D
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone) | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
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7Y5C
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
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7Y5A
| Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Wong, C.F, Saw, W.-G, Grueber, G. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
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7Y5B
| Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
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2I6V
| PDZ domain of EpsC from Vibrio cholerae, residues 219-305 | Descriptor: | General secretion pathway protein C | Authors: | Korotkov, K.V, Krumm, B, Bagdasarian, M, Hol, W.G.J. | Deposit date: | 2006-08-29 | Release date: | 2006-10-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae. J.Mol.Biol., 363, 2006
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2I4S
| PDZ domain of EpsC from Vibrio cholerae, residues 204-305 | Descriptor: | General secretion pathway protein C | Authors: | Korotkov, K.V, Krumm, B, Bagdasarian, M, Hol, W.G.J. | Deposit date: | 2006-08-22 | Release date: | 2006-10-17 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae. J.Mol.Biol., 363, 2006
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2JNR
| Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | Descriptor: | ENV polyprotein, VIR165 | Authors: | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | Deposit date: | 2007-02-01 | Release date: | 2007-05-08 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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2L6S
| Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide | Descriptor: | VIR-576 | Authors: | Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Canales-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Standker, L, Kirchhoff, F, Schmidt, R.E. | Deposit date: | 2010-11-24 | Release date: | 2011-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med, 2, 2010
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2L6T
| Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide | Descriptor: | VIR-576 | Authors: | Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E. | Deposit date: | 2010-11-24 | Release date: | 2011-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. Sci Transl Med, 2, 2010
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2LVI
| Solution structure of apo-Phl p 7 | Descriptor: | Polcalcin Phl p 7 | Authors: | Henzl, M.T, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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2LVJ
| solution structure of hemi-Mg-bound Phl p 7 | Descriptor: | MAGNESIUM ION, Polcalcin Phl p 7 | Authors: | Henzl, M.T, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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2LVK
| Solution structure of Ca-bound Phl p 7 | Descriptor: | CALCIUM ION, Polcalcin Phl p 7 | Authors: | Henzl, M.T, Sirianni, A.G, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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2MAD
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2NLU
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2N0X
| Three dimensional structure of EPI-X4, a human albumin-derived peptide that regulates innate immunity through the CXCR4/CXCL12 chemotactic axis and antagonizes HIV-1 entry | Descriptor: | Serum albumin | Authors: | Perez-Castells, J, Canales, A, Jimenez-Barbero, J, Gimenez-Gallego, G. | Deposit date: | 2015-03-18 | Release date: | 2015-04-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Discovery and characterization of an endogenous CXCR4 antagonist. Cell Rep, 11, 2015
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2ORA
| RHODANESE (THIOSULFATE: CYANIDE SULFURTRANSFERASE) | Descriptor: | OXIDIZED RHODANESE | Authors: | Gliubich, F, Gazerro, M, Zanotti, G, Delbono, S, Berni, R. | Deposit date: | 1996-02-22 | Release date: | 1996-08-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Active site structural features for chemically modified forms of rhodanese. J.Biol.Chem., 271, 1996
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3I7B
| Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor NM-PP1 | Descriptor: | 1,2-ETHANEDIOL, 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ... | Authors: | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2009-07-08 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.988 Å) | Cite: | Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat.Struct.Mol.Biol., 17, 2010
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3I7C
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3IBE
| Crystal Structure of a Pyrazolopyrimidine Inhibitor Bound to PI3 Kinase Gamma | Descriptor: | 1-(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}phenyl)-3-pyridin-4-ylurea, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Bard, J, Svenson, K. | Deposit date: | 2009-07-15 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines. J.Med.Chem., 52, 2009
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3I7F
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3IAL
| Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate | Descriptor: | 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, GLYCEROL, Prolyl-tRNA synthetase | Authors: | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2009-07-14 | Release date: | 2009-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia. Acta Crystallogr.,Sect.D, 68, 2012
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3I79
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3K80
| Structure of essential protein from Trypanosoma brucei | Descriptor: | Antibody, MP18 RNA editing complex protein | Authors: | Wu, M. | Deposit date: | 2009-10-13 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies. J.Struct.Biol., 174, 2011
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1KXI
| STRUCTURE OF CYTOTOXIN HOMOLOG PRECURSOR | Descriptor: | CARDIOTOXIN V | Authors: | Sun, Y.-J, Wu, W.-G, Chiang, C.-M, Hsin, A.-Y, Hsiao, C.-D. | Deposit date: | 1996-08-29 | Release date: | 1997-04-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structure of cardiotoxin V from Taiwan cobra venom: pH-dependent conformational change and a novel membrane-binding motif identified in the three-finger loops of P-type cardiotoxin. Biochemistry, 36, 1997
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