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6O9C
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BU of 6o9c by Molmil
Crystal structure of HLA-A3*01 in complex with a mutant beta-catenin peptide
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, Catenin beta-1, ...
Authors:Miller, M.S, Gabelli, S.B.
Deposit date:2019-03-13
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:An engineered antibody fragment targeting mutant beta-catenin via major histocompatibility complex I neoantigen presentation.
J.Biol.Chem., 294, 2019
7KGU
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BU of 7kgu by Molmil
Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Miller, M.S, Aytenfisu, T.Y, Wright, K.M, Gabelli, S.B.
Deposit date:2020-10-18
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
6UJ8
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BU of 6uj8 by Molmil
Crystal structure of HLA-B*07:02 with wild-type IDH2 peptide
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ...
Authors:Miller, M.S, Thirawatananond, P, Gabelli, S.B.
Deposit date:2019-10-02
Release date:2021-05-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
6UJ9
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BU of 6uj9 by Molmil
Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide in complex with Fab
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Miller, M.S, Thirawatananond, P, Aytenfisu, T.Y, Wright, K, Gabelli, S.B.
Deposit date:2019-10-02
Release date:2021-05-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
6UJ7
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BU of 6uj7 by Molmil
Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
Authors:Miller, M.S, Thirawatananond, P, Gabelli, S.B.
Deposit date:2019-10-02
Release date:2021-05-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
6W51
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BU of 6w51 by Molmil
Structure of the antibody fragment H2 in complex with HLA-A*02:01/p53R175H
Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, Immunoglobulin heavy chain H2, ...
Authors:Wright, K.M, Gabelli, S.B.
Deposit date:2020-03-12
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:Targeting a neoantigen derived from a common TP53 mutation.
Science, 371, 2021
1TUP
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BU of 1tup by Molmil
TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA
Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ...
Authors:Cho, Y, Gorina, S, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1995-07-11
Release date:1995-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
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