7CLX
 
 | | Crystal structure of the DOCK8 DHR-1 domain | | Descriptor: | Dedicator of cytokinesis protein 8 | | Authors: | Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S, Fukui, Y, Uruno, T. | | Deposit date: | 2020-07-22 | | Release date: | 2021-02-10 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8.
Life Sci Alliance, 4, 2021
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7CLY
 | | Structure of the DOCK8 DHR-1 domain crystallized with di-C8-phosphatidylinositol-(4,5)-bisphosphate | | Descriptor: | Dedicator of cytokinesis protein 8 | | Authors: | Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S, Fukui, Y, Uruno, T. | | Deposit date: | 2020-07-22 | | Release date: | 2021-02-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.432 Å) | | Cite: | A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8.
Life Sci Alliance, 4, 2021
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2RQR
 | | The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex | | Descriptor: | Engulfment and cell motility protein 1,Dedicator of cytokinesis protein 2 | | Authors: | Yokoyama, S, Tochio, N, Koshiba, S, Kigawa, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2009-10-21 | | Release date: | 2010-10-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VHL
 | | Crystal structure of the DHR-2 domain of DOCK8 in complex with Cdc42 (T17N mutant) | | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 8, PHOSPHATE ION | | Authors: | Hanawa-Suetsugu, K, Kukimoto-Niino, M, Nishizak, T, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. | | Deposit date: | 2011-08-26 | | Release date: | 2012-06-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.085 Å) | | Cite: | DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Blood, 119, 2012
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3B13
 | | Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant) | | Descriptor: | Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1 | | Authors: | Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. | | Deposit date: | 2011-06-24 | | Release date: | 2012-03-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.006 Å) | | Cite: | Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3A98
 | | Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 | | Authors: | Hanawa-Suetsugu, K, Kukimoto-Niino, M, Sekine, S, Ito, T, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. | | Deposit date: | 2009-10-21 | | Release date: | 2010-10-27 | | Last modified: | 2019-09-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2KZ7
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