7OOB
 
 | | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ... | | Authors: | Kokic, G, Cramer, P. | | Deposit date: | 2021-05-27 | | Release date: | 2021-10-13 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
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3GUD
 | | Crystal structure of a novel intramolecular chaperon | | Descriptor: | BROMIDE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Schulz, E.C, Dickmanns, A, Ficner, R. | | Deposit date: | 2009-03-29 | | Release date: | 2010-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding.
Nat.Struct.Mol.Biol., 17, 2010
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3GW6
 | | Intramolecular Chaperone | | Descriptor: | BROMIDE ION, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Schulz, E.C, Dickmanns, A, Ficner, R. | | Deposit date: | 2009-03-31 | | Release date: | 2010-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding.
Nat.Struct.Mol.Biol., 17, 2010
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8Q0N
 | | HACE1 in complex with RAC1 Q61L | | Descriptor: | E3 ubiquitin-protein ligase HACE1, GUANOSINE-5'-TRIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ... | | Authors: | Wolter, M, Duering, J, Dienemann, C, Lorenz, S. | | Deposit date: | 2023-07-28 | | Release date: | 2024-01-10 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024
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8PWL
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8RBX
 | | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-05 | | Release date: | 2024-02-07 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 2024
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8RC4
 | | Structure of Integrator-PP2A complex | | Descriptor: | DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-06 | | Release date: | 2024-02-07 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 2024
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8RBZ
 | | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | | Descriptor: | DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-05 | | Release date: | 2024-02-07 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 2024
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6QH3
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6QHK
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6QZV
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6QZW
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6RM9
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMB
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RFG
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6RMC
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | | Authors: | Hamann, F, Neumann, P, Schmitt, A, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMA
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RM8
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6S98
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6S96
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6TED
 | | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | | Authors: | Vos, S.M, Farnung, L, Cramer, P. | | Deposit date: | 2019-11-11 | | Release date: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
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8A3P
 | | Structure of human Fy-5. | | Descriptor: | Glutamine amidotransferase-like class 1 domain-containing protein 1 | | Authors: | Schuhmacher, J.S, Zerial, M. | | Deposit date: | 2022-06-08 | | Release date: | 2022-06-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of mRNA binding by the human FERRY Rab5 effector complex.
Mol.Cell, 83, 2023
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8A3O
 | | Structure of human Fy-4 | | Descriptor: | Quinone oxidoreductase-like protein 1 | | Authors: | Schuhmacher, J.S, Zerial, M. | | Deposit date: | 2022-06-08 | | Release date: | 2022-06-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of mRNA binding by the human FERRY Rab5 effector complex.
Mol.Cell, 83, 2023
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8C8H
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1XK5
 | | Crystal structure of the m3G-cap-binding domain of snurportin1 in complex with a m3GpppG-cap dinucleotide | | Descriptor: | 2,2,7-TRIMETHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, snurportin-1 | | Authors: | Strasser, A, Dickmanns, A, Luehrmann, R, Ficner, R. | | Deposit date: | 2004-09-27 | | Release date: | 2005-06-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1
Embo J., 24, 2005
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