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2JNR
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BU of 2jnr by Molmil
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide
Descriptor: ENV polyprotein, VIR165
Authors:Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F.
Deposit date:2007-02-01
Release date:2007-05-08
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide.
Cell(Cambridge,Mass.), 129, 2007
7SNT
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BU of 7snt by Molmil
2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine
Descriptor: (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine, Oplophorus-luciferin 2-monooxygenase catalytic subunit
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Unch, J, Encell, L.P, Wood, K.V.
Deposit date:2021-10-28
Release date:2022-11-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine
To be published
7C53
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BU of 7c53 by Molmil
Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor: CALCIUM ION, Spike protein S2',pan-CoVs inhibitor EK1
Authors:Zhu, Y, Yang, X, Sun, F.
Deposit date:2020-05-19
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Signal Transduct Target Ther, 6, 2021
8OKR
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BU of 8okr by Molmil
virus enhancing amyloid fibril formed by CKFKFQF
Descriptor: PNF-18
Authors:Heerde, T, Schmidt, M, Faendrich, M.
Deposit date:2023-03-29
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril.
Nat Commun, 14, 2023
2N0X
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BU of 2n0x by Molmil
Three dimensional structure of EPI-X4, a human albumin-derived peptide that regulates innate immunity through the CXCR4/CXCL12 chemotactic axis and antagonizes HIV-1 entry
Descriptor: Serum albumin
Authors:Perez-Castells, J, Canales, A, Jimenez-Barbero, J, Gimenez-Gallego, G.
Deposit date:2015-03-18
Release date:2015-04-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Discovery and characterization of an endogenous CXCR4 antagonist.
Cell Rep, 11, 2015
2L6S
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BU of 2l6s by Molmil
Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
Descriptor: VIR-576
Authors:Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Canales-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Standker, L, Kirchhoff, F, Schmidt, R.E.
Deposit date:2010-11-24
Release date:2011-01-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2L6T
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BU of 2l6t by Molmil
Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
Descriptor: VIR-576
Authors:Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E.
Deposit date:2010-11-24
Release date:2011-01-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
3PPD
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BU of 3ppd by Molmil
GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection
Descriptor: ACETIC ACID, GGVLVN peptide, amyloid forming segment, ...
Authors:Zhao, A, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-11-24
Release date:2011-06-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
Nature, 475, 2011

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