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3JZ4
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BU of 3jz4 by Molmil
Crystal structure of E. coli NADP dependent enzyme
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+]
Authors:Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C.
Deposit date:2009-09-22
Release date:2010-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
Plos One, 5, 2010
1YON
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BU of 1yon by Molmil
Escherichia coli ketopantoate reductase in complex with 2-monophosphoadenosine-5'-diphosphate
Descriptor: 2-dehydropantoate 2-reductase, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4R,5R)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
Authors:Ciulli, A, Lobley, C.M.C, Tuck, K.L, Williams, G, Smith, A.G, Blundell, T.L, Abell, C.
Deposit date:2005-01-28
Release date:2006-04-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:pH-tuneable binding of 2'-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study.
Acta Crystallogr.,Sect.D, 63, 2007
3VP6
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BU of 3vp6 by Molmil
Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
Descriptor: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1
Authors:Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C.
Deposit date:2012-02-27
Release date:2013-01-16
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep., 33, 2013
6NMB
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BU of 6nmb by Molmil
Tranexamic Acid is an Active Site Inhibitor of Urokinase Plasminogen Activator
Descriptor: NITRATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID, Urokinase-type plasminogen activator
Authors:Law, R.H.P, Wu, G.
Deposit date:2019-01-10
Release date:2019-03-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.
Blood Adv, 3, 2019
3COW
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BU of 3cow by Molmil
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution- in complex with sulphonamide inhibitor 2
Descriptor: 5'-O-{[(2R)-2-hydroxy-3,3-dimethylbutanoyl]sulfamoyl}adenosine, ETHANOL, GLYCEROL, ...
Authors:Ciulli, A, Chirgadze, D.Y, Blundell, T.L, Abell, C.
Deposit date:2008-03-29
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Chembiochem, 9, 2008
3COV
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BU of 3cov by Molmil
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.5 Ang resolution- apo form
Descriptor: ETHANOL, GLYCEROL, Pantothenate synthetase, ...
Authors:Ciulli, A, Chirgadze, D.Y, Blundell, T.L, Abell, C.
Deposit date:2008-03-29
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Chembiochem, 9, 2008
3COY
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BU of 3coy by Molmil
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.05 Ang resolution- in complex with sulphonamide inhibitor 3
Descriptor: 5'-O-[(3-methyl-D-valyl)sulfamoyl]adenosine, ETHANOL, GLYCEROL, ...
Authors:Ciulli, A, Chirgadze, D.Y, Blundell, T.L, Abell, C.
Deposit date:2008-03-29
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Chembiochem, 9, 2008
3COZ
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Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.0 Ang resolution- in complex with sulphonamide inhibitor 4
Descriptor: 5'-O-(D-valylsulfamoyl)adenosine, ETHANOL, GLYCEROL, ...
Authors:Ciulli, A, Chirgadze, D.Y, Blundell, T.L, Abell, C.
Deposit date:2008-03-29
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Chembiochem, 9, 2008

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