8JN6
 
 | | Cryo-EM structure of the small tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | Descriptor: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN3
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 37 deg C (subparticle LLR-LRR) | | Descriptor: | Envelope protein, Human antibody DENV-115 heavy chain, Human antibody DENV-115 light chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN7
 | | Cryo-EM structure of the big tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | Descriptor: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN5
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 37 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN4
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN2
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-115 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8JN1
 | | Cryo-EM structure of dengue virus serotype 3 strain EHIE46200Y19 in complex with human antibody DENV-115 IgG at 4 deg C (subparticle LLR-LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein (Fragment), Human antibody DENV-115 heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2023-06-06 | | Release date: | 2024-06-12 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
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8Y3H
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 N153Q mutant in complex with human antibody 2D22 Fab at 37 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody 2D22 Fab heavy chain, ... | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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8Y3K
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 in complex with human antibody 2D22 Fab at 37 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody 2D22 Fab (heavy chain), ... | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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8Y3I
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 N153Q mutant in complex with human antibody C10 Fab at 37 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody C10 Fab (heavy chain), ... | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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8Y3G
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 N153Q mutant at 4 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Membrane polyprotein | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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8Y3L
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 in complex with human antibody C10 Fab at 37 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody C10 Fab (heavy chain), ... | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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8Y3J
 | | Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 at 4 deg C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, ... | | Authors: | Fibriansah, G, Ng, T.S, Lim, X.N, Tan, A.W.K, Shi, J, Lok, S.M. | | Deposit date: | 2024-01-29 | | Release date: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Role of N-glycosylation at asparagine 153 of dengue envelope protein in immune response
To Be Published
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7Y72
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface) | | Descriptor: | Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein | | Authors: | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | Deposit date: | 2022-06-21 | | Release date: | 2023-08-02 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
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7Y71
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab E7 heavy chain, ... | | Authors: | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | Deposit date: | 2022-06-21 | | Release date: | 2023-08-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
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7V3F
 | | DENV2_NGC_Fab_C10 28degree (1Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3G
 | | DENV2_NGC_Fab_C10 28degrees (2Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3H
 | | DENV2_NGC_Fab_C10 28degrees (3Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3I
 | | DENV2_NGC_Fab_C10 4degrees (3Fab:3E) | | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3J
 | | DENV2:F(ab')2-local | | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7WUV
 | | CryoEM structure of sNS1 hexamer | | Descriptor: | Core protein | | Authors: | Shu, B, Ooi, J.S.G, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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7WUS
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7WUR
 | | CryoEM structure of sNS1 complexed with Fab5E3 | | Descriptor: | Core protein, Fab 5E3 Heavy Chain, Fab 5E3 Light Chain | | Authors: | Shu, B, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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7WUT
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7WUU
 | | CryoEM structure of loose sNS1 tetramer | | Descriptor: | Core protein | | Authors: | Shu, B, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (8.3 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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