4J8R
 
 | | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | | 分子名称: | Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein | | 著者 | Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G. | | 登録日 | 2013-02-14 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.
Protein Sci., 22, 2013
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4DGI
 | | Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230 | | 分子名称: | Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ... | | 著者 | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | | 登録日 | 2012-01-26 | | 公開日 | 2012-10-31 | | 最終更新日 | 2013-01-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta Crystallogr.,Sect.D, 68, 2012
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6AQ7
 | | Structure of POM6 FAB fragment complexed with mouse PrPc | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2017-08-18 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
FEBS J., 285, 2018
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4MA7
 | | Crystal structure of mouse prion protein complexed with Promazine | | 分子名称: | Major prion protein, POM1 heavy chain, POM1 light chain, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2013-08-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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4MA8
 | | Crystal structure of mouse prion protein complexed with Chlorpromazine | | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Major prion protein, POM1 heavy chain, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2013-08-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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4H88
 | | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | | 分子名称: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | | 著者 | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | | 登録日 | 2012-09-21 | | 公開日 | 2013-07-31 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Nature, 501, 2013
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4YX2
 | | Crystal structure of Bovine prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-22 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXL
 | | Crystal structure of Syrian hamster prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXH
 | | Crystal structure of Deer prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXK
 | | Crystal structure of Elk prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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