7T3O
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7T3N
| R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | 分子名称: | (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2 | 著者 | Li, F, Stroud, R.M, Edwards, R.H. | 登録日 | 2021-12-08 | 公開日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter To Be Published
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7ICD
| REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE | 分子名称: | ISOCITRATE DEHYDROGENASE | 著者 | Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M. | 登録日 | 1990-05-30 | 公開日 | 1991-10-15 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Regulation of an enzyme by phosphorylation at the active site. Science, 249, 1990
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3AID
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3BHS
| Nitrosomonas europaea Rh50 and mechanism of conduction by Rhesus protein family of channels | 分子名称: | Ammonium transporter family protein Rh50 | 著者 | Gruswitz, F, Ho, C.-M, del Rosario, M.C, Westhoff, C.M, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | 登録日 | 2007-11-29 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Nitrosomonas europaea Rh50 and mechanism of conduction by Rhesus protein family of channels. To be Published
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3BT7
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3C02
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3C4B
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | 分子名称: | Endoribonuclease Dicer | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | 登録日 | 2008-01-29 | 公開日 | 2008-02-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C4T
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | 分子名称: | CADMIUM ION, Endoribonuclease Dicer | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | 登録日 | 2008-01-30 | 公開日 | 2008-02-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1TGN
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2BH2
| Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine. | 分子名称: | 23S RIBOSOMAL RNA 1932-1968, 23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, IRON/SULFUR CLUSTER, ... | 著者 | Lee, T.T, Agarwalla, S, Stroud, R.M. | 登録日 | 2005-01-06 | 公開日 | 2005-03-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function Cell(Cambridge,Mass.), 120, 2005
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3P5S
| Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD38 molecule, SULFATE ION, ... | 著者 | Egea, P.F, Muller-Stauffler, H, Kohn, I, Cakou-Kefir, C, Stroud, R.M, Kellenberburger, E, Schuber, F. | 登録日 | 2010-10-10 | 公開日 | 2011-10-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One, 7, 2012
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4ICD
| REGULATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION INVOLVES NO LONG-RANGE CONFORMATIONAL CHANGE IN THE FREE ENZYME | 分子名称: | PHOSPHORYLATED ISOCITRATE DEHYDROGENASE | 著者 | Hurley, J.H, Dean, A.M, Thorsness, P.E, Koshlandjunior, D.E, Stroud, R.M. | 登録日 | 1989-12-28 | 公開日 | 1991-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme. J.Biol.Chem., 265, 1990
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7TBG
| AtTPC1 D454N with 1 mM Ca2+ | 分子名称: | CALCIUM ION, SODIUM ION, Two pore calcium channel protein 1 | 著者 | Dickinson, M.S, Stroud, R.M. | 登録日 | 2021-12-22 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
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3R1F
| Crystal structure of a key regulator of virulence in Mycobacterium tuberculosis | 分子名称: | ESX-1 secretion-associated regulator EspR | 著者 | Rosenberg, O.S, Dovey, C, Finer-Moore, J, Stroud, R.M, Cox, J.S. | 登録日 | 2011-03-10 | 公開日 | 2011-08-03 | 最終更新日 | 2011-08-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Proc.Natl.Acad.Sci.USA, 108, 2011
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2FFH
| THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS | 分子名称: | CADMIUM ION, PROTEIN (FFH), SULFATE ION | 著者 | Keenan, R.J, Freymann, D.M, Walter, P, Stroud, R.M. | 登録日 | 1999-06-29 | 公開日 | 1999-07-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell(Cambridge,Mass.), 94, 1998
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6C9W
| Crystal Structure of a ligand bound LacY/Nanobody Complex | 分子名称: | 4-nitrophenyl alpha-D-galactopyranoside, Lactose permease, Nanobody9047, ... | 著者 | Kumar, H, Finer-Moore, J.S, Jiang, X, Smirnova, I, Kasho, V, Pardon, E, Steyaert, J, Kaback, H.R, Stroud, R.M. | 登録日 | 2018-01-29 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of a ligand-bound LacY-Nanobody Complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6CX0
| Structure of AtTPC1 D376A | 分子名称: | (1S,3R)-1-(3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid, CALCIUM ION, Two pore calcium channel protein 1 | 著者 | Kintzer, A.F, Stroud, R.M. | 登録日 | 2018-04-02 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4E28
| Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor | 分子名称: | 2-{(2Z,5S)-4-hydroxy-2-[(2E)-(2-hydroxybenzylidene)hydrazinylidene]-2,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, 2-{(5S)-2-[(2E)-2-(2-hydroxybenzylidene)hydrazinyl]-4-oxo-4,5-dihydro-1,3-thiazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide, SULFATE ION, ... | 著者 | Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P. | 登録日 | 2012-03-07 | 公開日 | 2012-11-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase. J.Med.Chem., 55, 2012
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6E1M
| Structure of AtTPC1(DDE) reconstituted in saposin A | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1P
| Structure of AtTPC1(DDE) in state 2 | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1 | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1N
| Structure of AtTPC1(DDE) in state 1 | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1K
| Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | 登録日 | 2018-07-10 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E9N
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6E9O
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