3R1F
Crystal structure of a key regulator of virulence in Mycobacterium tuberculosis
Summary for 3R1F
| Entry DOI | 10.2210/pdb3r1f/pdb |
| Descriptor | ESX-1 secretion-associated regulator EspR (2 entities in total) |
| Functional Keywords | helix-turn-helix, transcription factor, helix-turn-helix transcription factor, transcription |
| Biological source | Mycobacterium tuberculosis |
| Cellular location | Secreted: P96228 |
| Total number of polymer chains | 18 |
| Total formula weight | 273393.04 |
| Authors | Rosenberg, O.S.,Dovey, C.,Finer-Moore, J.,Stroud, R.M.,Cox, J.S. (deposition date: 2011-03-10, release date: 2011-08-03, Last modification date: 2011-08-31) |
| Primary citation | Rosenberg, O.S.,Dovey, C.,Tempesta, M.,Robbins, R.A.,Finer-Moore, J.S.,Stroud, R.M.,Cox, J.S. EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Proc.Natl.Acad.Sci.USA, 108:13450-13455, 2011 Cited by PubMed: 21795602DOI: 10.1073/pnas.1110242108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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