3R1F

Crystal structure of a key regulator of virulence in Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009295	cellular_component	nucleoid
A	0042802	molecular_function	identical protein binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0050708	biological_process	regulation of protein secretion
A	0052572	biological_process	response to host immune response
B	0003677	molecular_function	DNA binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009295	cellular_component	nucleoid
B	0042802	molecular_function	identical protein binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0050708	biological_process	regulation of protein secretion
B	0052572	biological_process	response to host immune response
C	0003677	molecular_function	DNA binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0009295	cellular_component	nucleoid
C	0042802	molecular_function	identical protein binding
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0050708	biological_process	regulation of protein secretion
C	0052572	biological_process	response to host immune response
D	0003677	molecular_function	DNA binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0009295	cellular_component	nucleoid
D	0042802	molecular_function	identical protein binding
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0050708	biological_process	regulation of protein secretion
D	0052572	biological_process	response to host immune response
E	0003677	molecular_function	DNA binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0009295	cellular_component	nucleoid
E	0042802	molecular_function	identical protein binding
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0050708	biological_process	regulation of protein secretion
E	0052572	biological_process	response to host immune response
F	0003677	molecular_function	DNA binding
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0009295	cellular_component	nucleoid
F	0042802	molecular_function	identical protein binding
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0050708	biological_process	regulation of protein secretion
F	0052572	biological_process	response to host immune response
G	0003677	molecular_function	DNA binding
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0009295	cellular_component	nucleoid
G	0042802	molecular_function	identical protein binding
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0050708	biological_process	regulation of protein secretion
G	0052572	biological_process	response to host immune response
H	0003677	molecular_function	DNA binding
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0009295	cellular_component	nucleoid
H	0042802	molecular_function	identical protein binding
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0050708	biological_process	regulation of protein secretion
H	0052572	biological_process	response to host immune response
I	0003677	molecular_function	DNA binding
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0009274	cellular_component	peptidoglycan-based cell wall
I	0009295	cellular_component	nucleoid
I	0042802	molecular_function	identical protein binding
I	0045893	biological_process	positive regulation of DNA-templated transcription
I	0050708	biological_process	regulation of protein secretion
I	0052572	biological_process	response to host immune response
J	0003677	molecular_function	DNA binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0009274	cellular_component	peptidoglycan-based cell wall
J	0009295	cellular_component	nucleoid
J	0042802	molecular_function	identical protein binding
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0050708	biological_process	regulation of protein secretion
J	0052572	biological_process	response to host immune response
K	0003677	molecular_function	DNA binding
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0009274	cellular_component	peptidoglycan-based cell wall
K	0009295	cellular_component	nucleoid
K	0042802	molecular_function	identical protein binding
K	0045893	biological_process	positive regulation of DNA-templated transcription
K	0050708	biological_process	regulation of protein secretion
K	0052572	biological_process	response to host immune response
L	0003677	molecular_function	DNA binding
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0009274	cellular_component	peptidoglycan-based cell wall
L	0009295	cellular_component	nucleoid
L	0042802	molecular_function	identical protein binding
L	0045893	biological_process	positive regulation of DNA-templated transcription
L	0050708	biological_process	regulation of protein secretion
L	0052572	biological_process	response to host immune response
M	0003677	molecular_function	DNA binding
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0009274	cellular_component	peptidoglycan-based cell wall
M	0009295	cellular_component	nucleoid
M	0042802	molecular_function	identical protein binding
M	0045893	biological_process	positive regulation of DNA-templated transcription
M	0050708	biological_process	regulation of protein secretion
M	0052572	biological_process	response to host immune response
N	0003677	molecular_function	DNA binding
N	0005576	cellular_component	extracellular region
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0009274	cellular_component	peptidoglycan-based cell wall
N	0009295	cellular_component	nucleoid
N	0042802	molecular_function	identical protein binding
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0050708	biological_process	regulation of protein secretion
N	0052572	biological_process	response to host immune response
O	0003677	molecular_function	DNA binding
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0009274	cellular_component	peptidoglycan-based cell wall
O	0009295	cellular_component	nucleoid
O	0042802	molecular_function	identical protein binding
O	0045893	biological_process	positive regulation of DNA-templated transcription
O	0050708	biological_process	regulation of protein secretion
O	0052572	biological_process	response to host immune response
P	0003677	molecular_function	DNA binding
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0009274	cellular_component	peptidoglycan-based cell wall
P	0009295	cellular_component	nucleoid
P	0042802	molecular_function	identical protein binding
P	0045893	biological_process	positive regulation of DNA-templated transcription
P	0050708	biological_process	regulation of protein secretion
P	0052572	biological_process	response to host immune response
Q	0003677	molecular_function	DNA binding
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0009274	cellular_component	peptidoglycan-based cell wall
Q	0009295	cellular_component	nucleoid
Q	0042802	molecular_function	identical protein binding
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0050708	biological_process	regulation of protein secretion
Q	0052572	biological_process	response to host immune response
R	0003677	molecular_function	DNA binding
R	0005576	cellular_component	extracellular region
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0009274	cellular_component	peptidoglycan-based cell wall
R	0009295	cellular_component	nucleoid
R	0042802	molecular_function	identical protein binding
R	0045893	biological_process	positive regulation of DNA-templated transcription
R	0050708	biological_process	regulation of protein secretion
R	0052572	biological_process	response to host immune response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	DNA_BIND: H-T-H motif => ECO:0000255

Chain	Residue	Details
A	ILE38-SER50
J	ILE38-SER50
K	ILE38-SER50
L	ILE38-SER50
M	ILE38-SER50
N	ILE38-SER50
O	ILE38-SER50
P	ILE38-SER50
Q	ILE38-SER50
R	ILE38-SER50
B	ILE38-SER50
C	ILE38-SER50
D	ILE38-SER50
E	ILE38-SER50
F	ILE38-SER50
G	ILE38-SER50
H	ILE38-SER50
I	ILE38-SER50

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