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3LY7
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BU of 3ly7 by Molmil
Crystal structure of the periplasmic domain of CadC
Descriptor: Transcriptional activator cadC
Authors:Eichinger, A, Skerra, A.
Deposit date:2010-02-26
Release date:2011-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family.
Protein Sci., 20, 2011
3MBT
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BU of 3mbt by Molmil
Structure of monomeric Blc from E. coli
Descriptor: Outer membrane lipoprotein blc
Authors:Schiefner, A, Skerra, A.
Deposit date:2010-03-26
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical analyses reveal a monomeric state of the bacterial lipocalin Blc.
Acta Crystallogr.,Sect.D, 66, 2010
4QAF
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BU of 4qaf by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109)
Descriptor: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ...
Authors:Giese, T, Skerra, A.
Deposit date:2014-05-04
Release date:2015-05-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold
To be Published
4QAE
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BU of 4qae by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ...
Authors:Giese, T, Skerra, A.
Deposit date:2014-05-04
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a hepcidin-binding anticalin in complex with its peptide ligand
To be Published
4I5E
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BU of 4i5e by Molmil
Crystal structure of Ralstonia sp. alcohol dehydrogenase in complex with NADP+
Descriptor: Alclohol dehydrogenase/short-chain dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A.
Deposit date:2012-11-28
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol.Bioeng., 110, 2013
4I5D
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BU of 4i5d by Molmil
Crystal structure of Ralstonia sp. alcohol dehydrogenase in its apo form
Descriptor: Alclohol dehydrogenase/short-chain dehydrogenase, SULFATE ION
Authors:Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A.
Deposit date:2012-11-28
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol.Bioeng., 110, 2013
4I5F
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BU of 4i5f by Molmil
Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S
Descriptor: Alclohol dehydrogenase/short-chain dehydrogenase
Authors:Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A.
Deposit date:2012-11-28
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol.Bioeng., 110, 2013
4I5G
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BU of 4i5g by Molmil
Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S, A86N, S88A
Descriptor: Alclohol dehydrogenase/short-chain dehydrogenase
Authors:Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A.
Deposit date:2012-11-28
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol.Bioeng., 110, 2013
1KFF
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BU of 1kff by Molmil
An engineered streptavidin with improved affinity for the strep-tag II peptide: apo-SAM1
Descriptor: streptavidin
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2001-11-20
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL5
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BU of 1kl5 by Molmil
an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm2-StrepII
Descriptor: strep-tag II, streptavidin
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2001-12-11
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
4H8J
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BU of 4h8j by Molmil
Structure of GluA2-LBD in complex with MES
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutamate receptor 2, ...
Authors:Reiter, A, Skerra, A, Trauner, D, Schiefner, A.
Deposit date:2012-09-22
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of an artificial photoreceptor
To be Published
4H8I
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BU of 4h8i by Molmil
Structure of GluK2-LBD in complex with GluAzo
Descriptor: (4R)-4-[(2E)-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-en-1-yl]-L-glutamic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Reiter, A, Skerra, A, Trauner, D, Schiefner, A.
Deposit date:2012-09-22
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A photoswitchable neurotransmitter analogue bound to its receptor.
Biochemistry, 52, 2013
4GRX
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BU of 4grx by Molmil
Structure of an omega-aminotransferase from Paracoccus denitrificans
Descriptor: Aminotransferase, DELTA-AMINO VALERIC ACID, SODIUM ION
Authors:Rausch, C, Lerchner, A, Schiefner, A, Skerra, A.
Deposit date:2012-08-27
Release date:2012-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the omega-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential.
Proteins, 81, 2013
3KQ0
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BU of 3kq0 by Molmil
Crystal structure of human alpha1-acid glycoprotein
Descriptor: (2R)-2,3-dihydroxypropyl acetate, Alpha-1-acid glycoprotein 1, CHLORIDE ION
Authors:Schiefner, A, Schonfeld, D.L, Ravelli, R.B.G, Mueller, U, Skerra, A.
Deposit date:2009-11-17
Release date:2010-02-02
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin.
J.Mol.Biol., 384, 2008
1N0S
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BU of 1n0s by Molmil
ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Bilin-binding protein, SULFATE ION
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2002-10-15
Release date:2003-08-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region.
Proteins, 53, 2003
4GH7
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BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
Descriptor: Fibronectin, Neutrophil gelatinase-associated lipocalin
Authors:Schiefner, A, Gebauer, M, Skerra, A.
Deposit date:2012-08-07
Release date:2012-12-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
4HH8
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BU of 4hh8 by Molmil
Crystal structure of bovine butyrophilin
Descriptor: Butyrophilin subfamily 1 member A1
Authors:Eichinger, A, Skerra, A.
Deposit date:2012-10-09
Release date:2013-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The extracellular region of bovine butyrophilin exhibits high structural similarity to human myelin oligodendrocyte glycoprotein
To be Published
4IAW
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BU of 4iaw by Molmil
Engineered human lipocalin 2 (C26) in complex with Y-DTPA
Descriptor: N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION
Authors:Eichinger, A, Skerra, A.
Deposit date:2012-12-07
Release date:2013-06-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy
J.Struct.Biol., 185, 2014
4IAX
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BU of 4iax by Molmil
Engineered human lipocalin 2 (CL31) in complex with Y-DTPA
Descriptor: N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION
Authors:Eichinger, A, Skerra, A.
Deposit date:2012-12-07
Release date:2013-06-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy
J.Struct.Biol., 185, 2014
4IDF
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BU of 4idf by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HMF
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-5-methylfuran-3(2H)-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2012-12-12
Release date:2013-04-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDC
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BU of 4idc by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF
Descriptor: (2R)-4-hydroxy-2,5-dimethylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2012-12-12
Release date:2013-04-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDB
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BU of 4idb by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+
Descriptor: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ripening-induced protein, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2012-12-12
Release date:2013-04-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
4IDD
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BU of 4idd by Molmil
Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF
Descriptor: (2R)-2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2012-12-12
Release date:2013-04-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone
J.Biol.Chem., 288, 2013
2ICH
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BU of 2ich by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE ATTH (NE1406) FROM NITROSOMONAS EUROPAEA AT 2.00 A RESOLUTION
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Putative AttH, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-09-12
Release date:2006-10-03
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
8A6L
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BU of 8a6l by Molmil
Human 4F2hc-LAT2 heterodimeric amino acid transporter in complex with anticalin D11vs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2hc cell-surface antigen heavy chain, Anticalin D11vs, ...
Authors:Jeckelmann, J.M, Fotiadis, D.
Deposit date:2022-06-18
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM.
Sci Rep, 12, 2022

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數據於2024-05-22公開中

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