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7COM
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BU of 7com by Molmil
Crystal structure of the SARS-CoV-2 main protease in complex with Boceprevir (space group P212121)
Descriptor: 3C-like proteinase, boceprevir (bound form)
Authors:Zeng, R, Qiao, J.X, Wang, Y.F, Li, Y.S, Yao, R, Liu, J.M, Zhou, Y.L, Chen, P, Yang, S.Y, Lei, J.
Deposit date:2020-08-04
Release date:2020-08-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model.
Science, 371, 2021
2ND1
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BU of 2nd1 by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide
Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-19
Release date:2016-06-29
Last modified:2016-07-20
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
7D3I
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BU of 7d3i by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with MI-23
Descriptor: (3~{S},3~{a}~{S},6~{a}~{R})-2-[3-[3,5-bis(fluoranyl)phenyl]propanoyl]-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-3-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase
Authors:Zeng, R, Li, Y.S, Qiao, J.X, Wang, Y.F, Yang, S.Y, Lei, J.
Deposit date:2020-09-19
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model.
Science, 371, 2021
7D5K
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BU of 7d5k by Molmil
CryoEM structure of cotton cellulose synthase isoform 7
Descriptor: Cellulose synthase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Guan, Z.Y, Xue, Y, Yin, P, Zhang, X.L.
Deposit date:2020-09-26
Release date:2021-07-28
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into homotrimeric assembly of cellulose synthase CesA7 from Gossypium hirsutum.
Plant Biotechnol J, 19, 2021
5XJR
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BU of 5xjr by Molmil
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E/G from Human
Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
Authors:Yi, H, Zhang, R.
Deposit date:2017-05-04
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.
Nucleic Acids Res., 2019
5XJQ
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BU of 5xjq by Molmil
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2/F/E/G from Human
Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
Authors:Yi, H, Zhang, R.
Deposit date:2017-05-04
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.
Nucleic Acids Res., 2019
6BFN
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BU of 6bfn by Molmil
Crystal structure of human IRAK1
Descriptor: Interleukin-1 receptor-associated kinase 1, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
Authors:Wang, L, Qiao, Q, Wu, H.
Deposit date:2017-10-26
Release date:2017-12-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of human IRAK1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7LFH
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BU of 7lfh by Molmil
Cryo-EM structure of NLRP3 double-ring cage, 6-fold (12-mer)
Descriptor: NACHT, LRR and PYD domains-containing protein 3
Authors:Andreeva, L, Rawson, S, Wu, H.
Deposit date:2021-01-17
Release date:2021-12-15
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.
Cell, 184, 2021
7CRU
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BU of 7cru by Molmil
hnRNPK NLS in complex with Importin alpha 1 (KPNA2)
Descriptor: ACETATE ION, GLYCEROL, Heterogeneous nuclear ribonucleoprotein K, ...
Authors:Yao, J, Sun, Q.
Deposit date:2020-08-14
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Cell.Mol.Life Sci., 78, 2021
7CRE
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BU of 7cre by Molmil
hnRNPK KH3 domain in complex with a ssDNA fragment from the SIRLOIN element
Descriptor: Heterogeneous nuclear ribonucleoprotein K, SODIUM ION, ssDNA fragment
Authors:Yao, J, Sun, Q.
Deposit date:2020-08-13
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Cell.Mol.Life Sci., 78, 2021
6K8K
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BU of 6k8k by Molmil
Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex
Descriptor: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Wang, X, Ma, L, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6K8I
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BU of 6k8i by Molmil
Crystal structure of Arabidopsis thaliana CRY2
Descriptor: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Ma, L, Wang, X, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6N1H
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BU of 6n1h by Molmil
Cryo-EM structure of ASC-CARD filament
Descriptor: Apoptosis-associated speck-like protein containing a CARD
Authors:Li, Y, Fu, T, Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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