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8TZ5
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BU of 8tz5 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ2
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BU of 8tz2 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ9
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BU of 8tz9 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ3
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BU of 8tz3 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
5HY7
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BU of 5hy7 by Molmil
SF3B10-SF3B130 from Chaetomium thermophilum
分子名称: CALCIUM ION, Putative pre-mRNA splicing protein, YSF3
著者Ponce-Salvatierra, A, Schmitzova, J, Pena, V.
登録日2016-02-01
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Mol.Cell, 64, 2016
5IFE
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BU of 5ife by Molmil
Crystal structure of the human SF3b core complex
分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ...
著者Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V.
登録日2016-02-25
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Mol.Cell, 64, 2016
4BY6
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BU of 4by6 by Molmil
Yeast Not1-Not2-Not5 complex
分子名称: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Bhaskar, V, Basquin, J, Conti, E.
登録日2013-07-18
公開日2013-10-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Structure and RNA-Binding Properties of the not1-not2-not5 Module of the Yeast Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
4PCJ
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BU of 4pcj by Molmil
Modifications to toxic CUG RNAs induce structural stability and rescue mis-splicing in Myotonic Dystrophy
分子名称: MAGNESIUM ION, trCUG-3('5)
著者Coonrod, L.A, Reister, E.E, Berglund, J.A.
登録日2014-04-15
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.
Nucleic Acids Res., 42, 2014
4TXD
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BU of 4txd by Molmil
Crystal structure of Thermofilum pendens Csc2
分子名称: Csc2, ZINC ION
著者Hrle, A, Conti, E.
登録日2014-07-03
公開日2014-08-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.
Rna Biol., 11, 2014
4Z7L
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BU of 4z7l by Molmil
Crystal structure of Cas6b
分子名称: Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION
著者Li, H.
登録日2015-04-07
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Structure, 24, 2016
4Z7K
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BU of 4z7k by Molmil
Crystal structure of CRISPR RNA processing endoribonuclease Cas6b
分子名称: Cas6b, RNA/DNA Hybrid (31-MER)
著者Li, H.
登録日2015-04-07
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Structure, 24, 2016
7F71
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BU of 7f71 by Molmil
Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with peptidoglycan sugar moiety and glutamate
分子名称: GLUTAMIC ACID, GLYCEROL, L,D-transpeptidase 2, ...
著者Kumar, P, Lamichhane, G.
登録日2021-06-26
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase.
Elife, 11, 2022
7F8P
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BU of 7f8p by Molmil
Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with new carbapenem drug T203
分子名称: (2R,3R)-3-methyl-4-(2-oxidanylidene-2-propan-2-yloxy-ethyl)sulfanyl-2-[(2R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydro-1H-pyrrole-5-carboxylic acid, (4R,5S,6S)-6-((R)-1-hydroxyethyl)-3-((2-isopropoxy-2-oxoethyl)thio)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, GLUTAMIC ACID, ...
著者Kumar, P, Lamichhane, G.
登録日2021-07-02
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase.
Elife, 11, 2022
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件を2024-05-15に公開中

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