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7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
Descriptor: PBM, Sorting nexin-27
Authors:Shang, G.J, Qi, J.X.
Deposit date:2021-01-27
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
4N7S
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BU of 4n7s by Molmil
Crystal structure of Tse3-Tsi3 complex with Zinc ion
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Shang, G.J.
Deposit date:2013-10-16
Release date:2014-04-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
4N88
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BU of 4n88 by Molmil
Crystal structure of Tse3-Tsi3 complex with calcium ion
Descriptor: CALCIUM ION, Uncharacterized protein
Authors:Shang, G.J.
Deposit date:2013-10-17
Release date:2014-04-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
4N80
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BU of 4n80 by Molmil
Crystal structure of Tse3-Tsi3 complex
Descriptor: CALCIUM ION, Uncharacterized protein, ZINC ION
Authors:Shang, G.J.
Deposit date:2013-10-16
Release date:2014-04-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
6W36
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BU of 6w36 by Molmil
Crystal structure of FAM46C
Descriptor: SULFATE ION, Terminal nucleotidyltransferase 5C
Authors:Shang, G.J, Zhang, X.W, Chen, H, Lu, D.F.
Deposit date:2020-03-09
Release date:2020-05-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.854 Å)
Cite:Structural and Functional Analyses of the FAM46C/Plk4 Complex.
Structure, 28, 2020
8IK0
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BU of 8ik0 by Molmil
Cryo-EM structure of Stimulator of interferon genes
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
8IK3
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BU of 8ik3 by Molmil
Structure of Stimulator of interferon genes/ligand complex
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
6W38
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BU of 6w38 by Molmil
Crystal structure of the FAM46C/Plk4 complex
Descriptor: Serine/threonine-protein kinase PLK4, Terminal nucleotidyltransferase 5C
Authors:Chen, H, Lu, D.F, Shang, G.J, Zhang, X.W.
Deposit date:2020-03-09
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.48 Å)
Cite:Structural and Functional Analyses of the FAM46C/Plk4 Complex.
Structure, 28, 2020
6W3I
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BU of 6w3i by Molmil
Crystal structure of a FAM46C mutant in complex with Plk4
Descriptor: Serine/threonine-protein kinase PLK4, Terminal nucleotidyltransferase 5C
Authors:Chen, H, Shang, G.J, Lu, D.F, Zhang, X.W.
Deposit date:2020-03-09
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.802 Å)
Cite:Structural and Functional Analyses of the FAM46C/Plk4 Complex.
Structure, 28, 2020
6W3J
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BU of 6w3j by Molmil
Crystal structure of the FAM46C/Plk4/Cep192 complex
Descriptor: Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4, Terminal nucleotidyltransferase 5C
Authors:Chen, H, Lu, D.F, Shang, G.J, Zhang, X.W.
Deposit date:2020-03-09
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.385 Å)
Cite:Structural and Functional Analyses of the FAM46C/Plk4 Complex.
Structure, 28, 2020
6IYF
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BU of 6iyf by Molmil
Structure of pSTING complex
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, SULFATE ION, Stimulator of interferon genes protein
Authors:Yuan, Z.L, Shang, G.J, Cong, X.Y, Gu, L.C.
Deposit date:2018-12-15
Release date:2019-06-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294, 2019
6A06
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BU of 6a06 by Molmil
Structure of pSTING complex
Descriptor: SULFATE ION, Stimulator of interferon genes protein, cGAMP
Authors:Yuan, Z.L, Shang, G.J, Cong, X.Y, Gu, L.C.
Deposit date:2018-06-05
Release date:2019-06-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294, 2019
6A04
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BU of 6a04 by Molmil
Structure of pSTING complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION, Stimulator of interferon genes protein
Authors:Yuan, Z.L, Shang, G.J, Cong, X.Y, Gu, L.C.
Deposit date:2018-06-05
Release date:2019-06-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294, 2019
6A03
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BU of 6a03 by Molmil
Structure of pSTING complex
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, SULFATE ION, Stimulator of interferon genes protein
Authors:Yuan, Z.L, Shang, G.J, Cong, X.Y, Gu, L.C.
Deposit date:2018-06-05
Release date:2019-06-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294, 2019
6A05
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BU of 6a05 by Molmil
Structure of pSTING complex
Descriptor: 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, SULFATE ION, Stimulator of interferon genes protein
Authors:Yuan, Z.L, Shang, G.J, Cong, X.Y, Gu, L.C.
Deposit date:2018-06-05
Release date:2019-06-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
J.Biol.Chem., 294, 2019
6Q2R
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BU of 6q2r by Molmil
Cryo-EM structure of RET/GFRa2/NRTN extracellular complex in the tetrameric form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ...
Authors:Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
6PXV
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BU of 6pxv by Molmil
Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region.
Descriptor: Insulin, Insulin receptor
Authors:Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C.
Deposit date:2019-07-27
Release date:2019-09-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex.
Elife, 8, 2019
6Q2J
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BU of 6q2j by Molmil
Cryo-EM structure of extracellular dimeric complex of RET/GFRAL/GDF15
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-like, ...
Authors:Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
6Q2S
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BU of 6q2s by Molmil
Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2 symmetry.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-3, ...
Authors:Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
6Q2O
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BU of 6q2o by Molmil
Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ...
Authors:Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019
6PXW
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BU of 6pxw by Molmil
Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex.
Descriptor: Insulin, Insulin receptor
Authors:Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C.
Deposit date:2019-07-28
Release date:2019-09-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex.
Elife, 8, 2019
6Q2N
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BU of 6q2n by Molmil
Cryo-EM structure of RET/GFRa1/GDNF extracellular complex
Descriptor: CALCIUM ION, GDNF family receptor alpha-1, Glial cell line-derived neurotrophic factor, ...
Authors:Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C.
Deposit date:2019-08-08
Release date:2019-10-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife, 8, 2019

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