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4WDI
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BU of 4wdi by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2014-09-08
公開日2015-06-24
最終更新日2015-07-01
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
6FUQ
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BU of 6fuq by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Human F11 T-Cell Receptor, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2018-02-27
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FRB
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BU of 6frb by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
分子名称: Human T-Cell Receptor F11 alpha chain, Human T-Cell Receptor F11 beta Chain
著者Rizkallah, P.J, Cole, D.K.
登録日2018-02-15
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR6
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BU of 6fr6 by Molmil
HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101
分子名称: Human T-Cell Receptor Alpha Chain, Human T-cell Receptor Beta Chain, SULFATE ION
著者Rizkallah, P.J, Cole, D.K.
登録日2018-02-15
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUR
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BU of 6fur by Molmil
F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Human F11 T-Cell Receptor, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2018-02-27
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6QZD
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BU of 6qzd by Molmil
HLA-DR1 with SGP Influenza Matrix Peptide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6QZA
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BU of 6qza by Molmil
HLA-DR1 with GMF Influenza PB1 Peptide
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6R0E
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BU of 6r0e by Molmil
Structure of F11TCR in complex with DR1 MHC Class II presenting PKYVKQNTLKLAT
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, F11-TCR Alpha Chain, ...
著者Rizkallah, P.J, Greenshields-Watson, A.L.
登録日2019-03-12
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6QZC
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BU of 6qzc by Molmil
HLA-DR1 with the QAR Peptide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6TMO
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BU of 6tmo by Molmil
Structure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting a MART-1 peptide, EAAGIGILTV
分子名称: 1,2-ETHANEDIOL, Alpha chain of engineered high affinity T-cell receptor, Beta chain of high affinity engineered T-cell receptor, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2019-12-05
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy.
Mol Ther Oncolytics, 18, 2020
5N6B
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BU of 5n6b by Molmil
Human Leukocyte Antigen Class I A02 Carrying LLWNPGMAV
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Bulek, A.M, Bovay, A.
登録日2017-02-14
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus.
Eur. J. Immunol., 48, 2018
8CMC
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BU of 8cmc by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S511-530
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CME
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BU of 8cme by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Membrane peptide M176-190
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMI
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BU of 8cmi by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S761-775
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMF
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BU of 8cmf by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 nsp3 epitope (orf1ab)1350-1364
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMD
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BU of 8cmd by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S761-775
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMB
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BU of 8cmb by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S486-505
分子名称: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Mason, G.H, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMG
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BU of 8cmg by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 nsp14 peptide (orf1ab)6420-6434
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMH
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BU of 8cmh by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S486-505
分子名称: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
3IXA
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BU of 3ixa by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tax peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-09-03
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3KLA
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BU of 3kla by Molmil
Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Chen, J.L, Morgan, A.J, Stewart-Jones, G, Shepherd, D, Bossi, G, Wooldridge, L.
登録日2009-11-07
公開日2010-02-16
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor.
J.Immunol., 184, 2010
3H9S
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BU of 3h9s by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide
分子名称: A6 TCR alpha chain, Beta-2-microglobulin, GLYCEROL, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H7B
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BU of 3h7b by Molmil
Human Class I MHC HLA-A2 in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-24
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9H
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BU of 3h9h by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
4Z78
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BU of 4z78 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2015-04-06
公開日2015-06-24
最終更新日2015-08-12
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015

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件を2024-05-15に公開中

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