1WUF
 
 | | Crystal structure of protein GI:16801725, member of Enolase superfamily from Listeria innocua Clip11262 | | 分子名称: | MAGNESIUM ION, hypothetical protein lin2664 | | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-12-07 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family
Proc.Natl.Acad.Sci.USA, 111, 2014
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3DKF
 | | Structure of MET receptor tyrosine kinase in complex with inhibitor SGX-523 | | 分子名称: | 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline, CHLORIDE ION, Hepatocyte growth factor receptor | | 著者 | Hendle, J. | | 登録日 | 2008-06-24 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Mol.Cancer Ther., 8, 2009
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3DKC
 | | Structure of MET receptor tyrosine kinase in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Hepatocyte growth factor receptor, ... | | 著者 | Hendle, J. | | 登録日 | 2008-06-24 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Mol.Cancer Ther., 8, 2009
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3DKG
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2OUX
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2PAJ
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2PGE
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2QS8
 | | Crystal structure of a Xaa-Pro dipeptidase with bound methionine in the active site | | 分子名称: | MAGNESIUM ION, METHIONINE, Xaa-Pro Dipeptidase | | 著者 | Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-07-30 | | 公開日 | 2007-08-21 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes.
Biochemistry, 48, 2009
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2QJC
 | | Crystal structure of a putative diadenosine tetraphosphatase | | 分子名称: | Diadenosine tetraphosphatase, putative, MANGANESE (II) ION, ... | | 著者 | Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-07-06 | | 公開日 | 2007-07-24 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
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3HPF
 | | Crystal structure of the mutant Y90F of divergent galactarate dehydratase from Oceanobacillus iheyensis complexed with Mg and galactarate | | 分子名称: | D-galactaric acid, MAGNESIUM ION, Muconate cycloisomerase | | 著者 | Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Gerlt, J.A, Almo, S.C. | | 登録日 | 2009-06-04 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis .
Biochemistry, 48, 2009
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3HPA
 | | Crystal structure of an amidohydrolase gi:44264246 from an evironmental sample of sargasso sea | | 分子名称: | AMIDOHYDROLASE, ZINC ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Toro, R, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-06-03 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The hunt for 8-oxoguanine deaminase.
J.Am.Chem.Soc., 132, 2010
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3KXW
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3LKB
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3LNV
 | | The crystal structure of fatty acyl-adenylate ligase from L. pneumophila in complex with acyl adenylate and pyrophosphate | | 分子名称: | 5'-O-[(S)-(dodecanoyloxy)(hydroxy)phosphoryl]adenosine, PYROPHOSPHATE 2-, Saframycin Mx1 synthetase B | | 著者 | Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-02-03 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila.
J.Mol.Biol., 406, 2011
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3LY0
 | | Crystal structure of metallo peptidase from Rhodobacter sphaeroides liganded with phosphinate mimic of dipeptide L-Ala-D-Ala | | 分子名称: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, Dipeptidase AC. Metallo peptidase. MEROPS family M19, ZINC ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Cummings, J, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-02-25 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Crystal structure of metallo peptidase from Rhodobacter sphaeroides
liganded with phosphinate mimic of dipeptide L-Ala-D-Ala
To be Published
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3M3P
 | | Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus | | 分子名称: | Glutamine amido transferase | | 著者 | Fedorov, A.A, Domagalski, M, Fedorov, E.V, Burley, S.K, Minor, W, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-03-09 | | 公開日 | 2010-03-23 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus
To be Published
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3MTW
 | | Crystal structure of L-Lysine, L-Arginine carboxypeptidase Cc2672 from Caulobacter Crescentus CB15 complexed with N-methyl phosphonate derivative of L-Arginine | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, L-Arginine carboxypeptidase Cc2672, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Xiang, D.F, Raushel, F.M, Almo, S.C. | | 登録日 | 2010-05-01 | | 公開日 | 2010-07-28 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Functional Identification and Structure Determination of Two Novel Prolidases from cog1228 in the Amidohydrolase Superfamily
Biochemistry, 49, 2010
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3FCP
 | | Crystal structure of Muconate lactonizing enzyme from Klebsiella pneumoniae | | 分子名称: | L-Ala-D/L-Glu epimerase, a muconate lactonizing enzyme, MAGNESIUM ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-11-22 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Muconate lactonizing enzyme from Klebsiella pneumoniae
To be Published
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3CAW
 | | Crystal structure of o-succinylbenzoate synthase from Bdellovibrio bacteriovorus liganded with Mg | | 分子名称: | MAGNESIUM ION, o-succinylbenzoate synthase | | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-02-20 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3D8K
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3DG6
 | | Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone | | 分子名称: | MAGNESIUM ION, Muconate cycloisomerase, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid | | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Gerlt, J.A, Almo, S.C. | | 登録日 | 2008-06-12 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes
Biochemistry, 48, 2009
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3DG7
 | | Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone | | 分子名称: | MAGNESIUM ION, Muconate cycloisomerase, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid | | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Gerlt, J.A, Almo, S.C. | | 登録日 | 2008-06-12 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes
Biochemistry, 48, 2009
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3DG3
 | | Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis | | 分子名称: | MAGNESIUM ION, Muconate cycloisomerase | | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Gerlt, J.A, Almo, S.C. | | 登録日 | 2008-06-12 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes
Biochemistry, 48, 2009
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3FM3
 | | Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 | | 分子名称: | FE (III) ION, Methionine aminopeptidase 2, SULFATE ION | | 著者 | Alvarado, J.J, Russell, M, Zhang, A, Adams, J, Toro, R, Burley, S.K, Weiss, L.M, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-12-19 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
Mol.Biochem.Parasitol., 168, 2009
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3FMQ
 | | Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor fumagillin bound | | 分子名称: | FE (III) ION, FUMAGILLIN, Methionine aminopeptidase 2, ... | | 著者 | Alvarado, J.J, Russell, M, Zhang, A, Adams, J, Toro, R, Burley, S.K, Weiss, L.M, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-12-22 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.
Mol.Biochem.Parasitol., 168, 2009
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