3DG6

Crystal structure of muconate lactonizing enzyme from Mucobacterium Smegmatis complexed with muconolactone

Summary for 3DG6

Entry DOI	10.2210/pdb3dg6/pdb
Related	3DG3 3DG7
Descriptor	Muconate cycloisomerase, MAGNESIUM ION, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid, ... (4 entities in total)
Functional Keywords	muconate lactonizing enzyme, muconolactone binding, isomerase
Biological source	Mycobacterium smegmatis
Total number of polymer chains	1
Total formula weight	40185.94
Authors	Fedorov, A.A.,Fedorov, E.V.,Sakai, A.,Gerlt, J.A.,Almo, S.C. (deposition date: 2008-06-12, release date: 2009-03-03, Last modification date: 2024-03-20)
Primary citation	Sakai, A.,Fedorov, A.A.,Fedorov, E.V.,Schnoes, A.M.,Glasner, M.E.,Brown, S.,Rutter, M.E.,Bain, K.,Chang, S.,Gheyi, T.,Sauder, J.M.,Burley, S.K.,Babbitt, P.C.,Almo, S.C.,Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry, 48:1445-1453, 2009 Cited by PubMed: 19220063 DOI: 10.1021/bi802277h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation