3FMQ
Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor fumagillin bound
Replaces: 3CMKSummary for 3FMQ
Entry DOI | 10.2210/pdb3fmq/pdb |
Related | 3FM3 3FMR |
Descriptor | Methionine aminopeptidase 2, FE (III) ION, FUMAGILLIN, ... (5 entities in total) |
Functional Keywords | methionine aminopeptidase type2, metap2, metap2 fumagillin complex, encephalitozoon cuniculi, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, aminopeptidase, cobalt, hydrolase, metal-binding, protease |
Biological source | Encephalitozoon cuniculi |
Total number of polymer chains | 2 |
Total formula weight | 81491.57 |
Authors | Alvarado, J.J.,Russell, M.,Zhang, A.,Adams, J.,Toro, R.,Burley, S.K.,Weiss, L.M.,Almo, S.C.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2008-12-22, release date: 2009-01-13, Last modification date: 2023-09-06) |
Primary citation | Alvarado, J.J.,Nemkal, A.,Sauder, J.M.,Russell, M.,Akiyoshi, D.E.,Shi, W.,Almo, S.C.,Weiss, L.M. Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470. Mol.Biochem.Parasitol., 168:158-167, 2009 Cited by PubMed: 19660503DOI: 10.1016/j.molbiopara.2009.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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