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7N5E
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BU of 7n5e by Molmil
Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
7N5F
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BU of 7n5f by Molmil
Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
5WO9
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BU of 5wo9 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6* in the presence of Calcium
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, Sobolevsky, A.I.
Deposit date:2017-08-01
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WO8
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BU of 5wo8 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*-Del1
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, Sobolevsky, A.I.
Deposit date:2017-08-01
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WOA
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BU of 5woa by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6* in the presence of Gadolinium
Descriptor: GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, Sobolevsky, A.I.
Deposit date:2017-08-01
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.899 Å)
Cite:Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WO7
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BU of 5wo7 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, Sobolevsky, A.I.
Deposit date:2017-08-01
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.246 Å)
Cite:Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
5WO6
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BU of 5wo6 by Molmil
Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6cryst
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, Sobolevsky, A.I.
Deposit date:2017-08-01
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
6MGV
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BU of 6mgv by Molmil
Structure of mechanically activated ion channel OSCA1.2 in nanodisc
Descriptor: Calcium permeable stress-gated cation channel 1
Authors:Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
Deposit date:2018-09-15
Release date:2018-11-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
6MGW
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BU of 6mgw by Molmil
Structure of mechanically activated ion channel OSCA1.2 in LMNG
Descriptor: Calcium permeable stress-gated cation channel 1
Authors:Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
Deposit date:2018-09-15
Release date:2018-11-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
6D7V
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BU of 6d7v by Molmil
Crystal Structure of Rat TRPV6*- in complex with brominated 2-Aminoethoxydiphenyl borate (2-APB-Br)
Descriptor: 2-aminoethyl (4-bromophenyl)phenylborinate, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7S
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BU of 6d7s by Molmil
Cryo-EM structure of human TRPV6-Y467A in amphipols
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7P
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BU of 6d7p by Molmil
Crystal Structure of Rat TRPV6*-Y466A
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7Q
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BU of 6d7q by Molmil
Crystal Structure of Rat TRPV6*-Y466A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Descriptor: 2-aminoethyl diphenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ...
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.497 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7X
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BU of 6d7x by Molmil
Crystal Structure of Rat TRPV6*-Y466A- in complex with brominated 2-Aminoethoxydiphenyl borate (2-APB-Br)
Descriptor: 2-aminoethyl (4-bromophenyl)phenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ...
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7O
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BU of 6d7o by Molmil
Crystal Structure of Rat TRPV6* in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Descriptor: 2-aminoethyl diphenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ...
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7T
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BU of 6d7t by Molmil
Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Descriptor: 2-aminoethyl diphenylborinate, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-04-25
Release date:2018-07-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.44 Å)
Cite:Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6DJB
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BU of 6djb by Molmil
Structure of human Volume Regulated Anion Channel composed of SWELL1 (LRRC8A)
Descriptor: Volume-regulated anion channel subunit LRRC8A
Authors:Kefauver, J.M, Saotome, K, Pallesen, J, Cottrell, C.A, Ward, A.B, Patapoutian, A.
Deposit date:2018-05-24
Release date:2018-08-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of the human volume regulated anion channel.
Elife, 7, 2018
6BO8
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BU of 6bo8 by Molmil
Cryo-EM structure of human TRPV6 in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
Deposit date:2017-11-18
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
6BOB
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BU of 6bob by Molmil
Cryo-EM structure of rat TRPV6* in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
Deposit date:2017-11-18
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
6BO9
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BU of 6bo9 by Molmil
Cryo-EM structure of human TRPV6 in amphipols
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
Deposit date:2017-11-18
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
6BOA
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BU of 6boa by Molmil
Cryo-EM structure of human TRPV6-R470E in amphipols
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I.
Deposit date:2017-11-18
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
8D7H
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BU of 8d7h by Molmil
Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D82
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BU of 8d82 by Molmil
Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7E
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BU of 8d7e by Molmil
Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor receptor subunit alpha, H4H25311P2 antibody Fab fragment heavy chain, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7R
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BU of 8d7r by Molmil
Cryo-EM structure of human CLCF1 signaling complex: model containing the interaction core region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023

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