6D7V
Crystal Structure of Rat TRPV6*- in complex with brominated 2-Aminoethoxydiphenyl borate (2-APB-Br)
Summary for 6D7V
| Entry DOI | 10.2210/pdb6d7v/pdb |
| Descriptor | Transient receptor potential cation channel subfamily V member 6, 2-aminoethyl (4-bromophenyl)phenylborinate, CALCIUM ION (3 entities in total) |
| Functional Keywords | ion channels, transporter, calcium channel, epithelial calcium channel, membrane protein, membrane protein-inhibitor complex, membrane protein/inhibitor |
| Biological source | Rattus norvegicus (Rat) |
| Total number of polymer chains | 1 |
| Total formula weight | 77477.56 |
| Authors | Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I. (deposition date: 2018-04-25, release date: 2018-07-18, Last modification date: 2023-10-04) |
| Primary citation | Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I. Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9:2465-2465, 2018 Cited by PubMed: 29941865DOI: 10.1038/s41467-018-04828-y PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.3 Å) |
Structure validation
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