Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4UX8
DownloadVisualize
BU of 4ux8 by Molmil
RET recognition of GDNF-GFRalpha1 ligand by a composite binding site promotes membrane-proximal self-association
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF FAMILY RECEPTOR ALPHA-1, ...
Authors:Goodman, K, Kjaer, S, Beuron, F, Knowles, P, Nawrotek, A, Burns, E, Purkiss, A, George, R, Santoro, M, Morris, E.P, McDonald, N.Q.
Deposit date:2014-08-19
Release date:2014-10-01
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (24 Å)
Cite:Ret Recognition of Gdnf-Gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association.
Cell Rep., 8, 2014
4X9U
DownloadVisualize
BU of 4x9u by Molmil
Crystal structure of the kiwifruit allergen Act d 5
Descriptor: Kiwellin
Authors:Offermann, L.R, Perdue, M.L, Giangrieco, I, Tamburrini, M, Ciardiello, M.A, Chruszcz, M.
Deposit date:2014-12-11
Release date:2015-07-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Elusive Structural, Functional, and Immunological Features of Act d 5, the Green Kiwifruit Kiwellin.
J.Agric.Food Chem., 63, 2015
7NZN
DownloadVisualize
BU of 7nzn by Molmil
Structure of RET kinase domain bound to inhibitor JB-48
Descriptor: 2-[4-[[4-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-6-[(3-methyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]-~{N}-(3-fluorophenyl)ethanamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
Authors:Briggs, D.C, McDonald, N.Q.
Deposit date:2021-03-24
Release date:2022-02-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
J.Med.Chem., 65, 2022
2IVS
DownloadVisualize
BU of 2ivs by Molmil
Crystal structure of non-phosphorylated RET tyrosine kinase domain
Descriptor: 2',3'- cyclic AMP, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Chemical Inhibition of the Ret Tyrosine Kinase Domain.
J.Biol.Chem., 281, 2006
2IVT
DownloadVisualize
BU of 2ivt by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain
Descriptor: ADENOSINE MONOPHOSPHATE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
2IVV
DownloadVisualize
BU of 2ivv by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor PP1
Descriptor: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
2IVU
DownloadVisualize
BU of 2ivu by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD6474
Descriptor: FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR, Vandetanib
Authors:Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
Deposit date:2006-06-16
Release date:2006-08-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon