7X7O
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![BU of 7x7o by Molmil](/molmil-images/mine/7x7o) | SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K | Descriptor: | Spike protein S1, UT28K Fab, heavy chain, ... | Authors: | Ozawa, T, Tani, H, Anraku, Y, Kita, S, Igarashi, E, Saga, Y, Inasaki, N, Kawasuji, H, Yamada, H, Sasaki, S, Somekawa, M, Sasaki, J, Hayakawa, Y, Yamamoto, Y, Morinaga, Y, Kurosawa, N, Isobe, M, Fukuhara, H, Maenaka, K, Hashiguchi, T, Kishi, H, Kitajima, I, Saito, S, Niimi, H. | Deposit date: | 2022-03-10 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants. Mabs, 14, 2022
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8H7X
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![BU of 8h7x by Molmil](/molmil-images/mine/8h7x) | Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib | Descriptor: | 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor | Authors: | Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2022-10-21 | Release date: | 2023-10-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.404 Å) | Cite: | A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer. NPJ Precis Oncol, 8, 2024
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1X1D
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![BU of 1x1d by Molmil](/molmil-images/mine/1x1d) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine and Zn-bacteriopheophorbide d | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-04 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
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1X1B
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![BU of 1x1b by Molmil](/molmil-images/mine/1x1b) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
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8K5G
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![BU of 8k5g by Molmil](/molmil-images/mine/8k5g) | |
8K5H
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![BU of 8k5h by Molmil](/molmil-images/mine/8k5h) | Structure of the SARS-CoV-2 BA.1 spike with UT28-RD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Chen, L, Kita, S, Anraku, Y, Maenaka, K. | Deposit date: | 2023-07-21 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | In silico-designed UT28K with two amino acid substitutions is capable of neutralization of resistant SARS-CoV2 Omicrons BA.1 valiant. To Be Published
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1X19
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![BU of 1x19 by Molmil](/molmil-images/mine/1x19) | Crystal structure of BchU involved in bacteriochlorophyll c biosynthesis | Descriptor: | CrtF-related protein, SULFATE ION | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-02 | Release date: | 2006-07-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
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1X1A
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![BU of 1x1a by Molmil](/molmil-images/mine/1x1a) | Crystal structure of BchU complexed with S-adenosyl-L-methionine | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYLMETHIONINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
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1X1C
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![BU of 1x1c by Molmil](/molmil-images/mine/1x1c) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine and Zn2+ | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
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