8K5G

Structure of the SARS-CoV-2 BA.1 RBD with UT28-RD

Summary for 8K5G

Entry DOI	10.2210/pdb8k5g/pdb
EMDB information	36905
Descriptor	UT28K-RD Fab Heavy chain, UT28K-RD Fab Light chain, Spike protein S1 (3 entities in total)
Functional Keywords	sars-cov-2, antibody, spike protein, structural protein, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	78366.09
Authors	Chen, L.,Kita, S.,Anraku, Y.,Maenaka, K. (deposition date: 2023-07-21, release date: 2023-12-27)
Primary citation	Ozawa, T.,Ikeda, Y.,Chen, L.,Suzuki, R.,Hoshino, A.,Noguchi, A.,Kita, S.,Anraku, Y.,Igarashi, E.,Saga, Y.,Inasaki, N.,Taminishi, S.,Sasaki, J.,Kirita, Y.,Fukuhara, H.,Maenaka, K.,Hashiguchi, T.,Fukuhara, T.,Hirabayashi, K.,Tani, H.,Kishi, H.,Niimi, H. In silico-designed UT28K with two amino acid substitutions is capable of neutralization of resistant SARS-CoV2 Omicrons BA.1 valiant. To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.41 Å)

Structure validation