8K5H

Structure of the SARS-CoV-2 BA.1 spike with UT28-RD

Summary for 8K5H

• Entry DOI: 10.2210/pdb8k5h/pdb
• EMDB information: 36906
• Descriptor: Spike glycoprotein, UT28K-RD Fab heavy chain, UT28K-RD Fab light chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2, antibody, spike protein, structural protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2); More
• Total number of polymer chains: 5
• Total formula weight: 463435.17

Authors

Chen, L.,Kita, S.,Anraku, Y.,Maenaka, K. (deposition date: 2023-07-21, release date: 2023-12-27)

• Primary citation: Ozawa, T.,Ikeda, Y.,Chen, L.,Suzuki, R.,Hoshino, A.,Noguchi, A.,Kita, S.,Anraku, Y.,Igarashi, E.,Saga, Y.,Inasaki, N.,Taminishi, S.,Sasaki, J.,Kirita, Y.,Fukuhara, H.,Maenaka, K.,Hashiguchi, T.,Fukuhara, T.,Hirabayashi, K.,Tani, H.,Kishi, H.,Niimi, H.; In silico-designed UT28K with two amino acid substitutions is capable of neutralization of resistant SARS-CoV2 Omicrons BA.1 valiant.; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.22 Å)