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Structure of heteromeric amyloid filament of TDP-43 and AXNA11 from FTLD-TDP Type C (variant 1)
Descriptor:	Annexin A11, TAR DNA-binding protein 43
Authors:	Arseni, D, Ryskeldi-Falcon, B.
Deposit date:	2024-06-12
Release date:	2024-07-24
Method:	ELECTRON MICROSCOPY (2.75 Å)
Cite:	Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C. Biorxiv, 2024

9FOF

Structure of heteromeric amyloid filament of TDP-43 and AXNA11 from FTLD-TDP Type C (variant 2)
Descriptor:	Annexin A11, TAR DNA-binding protein 43
Authors:	Arseni, D, Ryskeldi-Falcon, B.
Deposit date:	2024-06-11
Release date:	2024-07-24
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C. Biorxiv, 2024

8BGS

Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain
Descriptor:	Microtubule-associated protein tau
Authors:	Behr, T.S, Ryskeldi-Falcon, B.
Deposit date:	2022-10-28
Release date:	2023-05-24
Last modified:	2024-07-24
Method:	ELECTRON MICROSCOPY (3.16 Å)
Cite:	Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease. Biorxiv, 2023

8BGV

Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain
Descriptor:	Microtubule-associated protein tau
Authors:	Behr, T.S, Ryskeldi-Falcon, B.
Deposit date:	2022-10-28
Release date:	2023-05-24
Last modified:	2024-07-24
Method:	ELECTRON MICROSCOPY (3.27 Å)
Cite:	Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease. Biorxiv, 2023

8CG3

Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
Descriptor:	TAR DNA-binding protein 43
Authors:	Arseni, D, Ryskeldi-Falcon, B.
Deposit date:	2023-02-03
Release date:	2023-08-02
Last modified:	2023-08-30
Method:	ELECTRON MICROSCOPY (2.39 Å)
Cite:	TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023

8CGG

Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
Descriptor:	TAR DNA-binding protein 43
Authors:	Arseni, D, Ryskeldi-Falcon, B.
Deposit date:	2023-02-04
Release date:	2023-08-02
Last modified:	2023-08-30
Method:	ELECTRON MICROSCOPY (2.5 Å)
Cite:	TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023

8CGH

Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
Descriptor:	TAR DNA-binding protein 43
Authors:	Arseni, D, Ryskeldi-Falcon, B.
Deposit date:	2023-02-04
Release date:	2023-08-02
Last modified:	2023-08-30
Method:	ELECTRON MICROSCOPY (2.68 Å)
Cite:	TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023

8ONS

TAF15 amyloid fold in atypical FTLD - Individual 1
Descriptor:	TATA-binding protein-associated factor 2N
Authors:	Tetter, S, Ryskeldi-Falcon, B.
Deposit date:	2023-04-03
Release date:	2023-12-06
Last modified:	2024-02-07
Method:	ELECTRON MICROSCOPY (1.97 Å)
Cite:	TAF15 amyloid filaments in frontotemporal lobar degeneration. Nature, 625, 2024

8OTI

CTE typeIII tau filament
Descriptor:	Microtubule-associated protein tau
Authors:	Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

7Q4M

Type II beta-amyloid 42 Filaments from Human Brain
Descriptor:	Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:	Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:	2021-11-01
Release date:	2021-11-24
Last modified:	2024-07-17
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Cryo-EM structures of amyloid-beta 42 filaments from human brains. Science, 375, 2022

7Q4B

Type I beta-amyloid 42 Filaments from Human Brain
Descriptor:	Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:	Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:	2021-10-30
Release date:	2021-11-24
Last modified:	2024-07-17
Method:	ELECTRON MICROSCOPY (2.5 Å)
Cite:	Cryo-EM structures of amyloid-beta 42 filaments from human brains. Science, 375, 2022

7QWL

TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-25
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (3.47 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QVF

TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-21
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (3.64 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QVC

TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-21
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (2.64 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QWG

TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-25
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (3.38 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QWM

TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-25
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (2.76 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7PY2

Structure of pathological TDP-43 filaments from ALS with FTLD
Descriptor:	TAR DNA-binding protein 43
Authors:	Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B.
Deposit date:	2021-10-08
Release date:	2021-12-15
Last modified:	2024-07-17
Method:	ELECTRON MICROSCOPY (2.59 Å)
Cite:	Structure of pathological TDP-43 filaments from ALS with FTLD. Nature, 601, 2022

8OT9

CTE typeIII tau filament from Guam ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTD

TMEM106B Fold1-s filament from Guam ALS/PDC
Descriptor:	Transmembrane protein 106B
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (2.6 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTF

Ab typeII filament from Guam ALS/PDC
Descriptor:	Amyloid-beta precursor protein
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTG

CTE typeI tau filament from Kii ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (2.1 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTH

TypeII tau filament from Kii ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTC

CTE typeII tau filament from Guam ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OTJ

PHF tau filament from Kii ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

8OT6

CTE typeI tau filament from Guam ALS/PDC
Descriptor:	Microtubule-associated protein tau
Authors:	Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:	2023-04-20
Release date:	2024-03-27
Method:	ELECTRON MICROSCOPY (2 Å)
Cite:	Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023

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Total results:	26
Displayed results:	25
Sorted by:	Hit score (from highest)