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4XX3
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BU of 4xx3 by Molmil
Renin in complex with (S)-1-(3-(benzylcarbamoyl)benzyl)-4-isopropyl-4-methyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-benzyl-3-{[(2Z,4S)-2-imino-4-methyl-6-oxo-4-(propan-2-yl)tetrahydropyrimidin-1(2H)-yl]methyl}benzamide, Renin
Authors:Orth, P.
Deposit date:2015-01-29
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
Bioorg. Med. Chem. Lett., 25, 2015
7RRO
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BU of 7rro by Molmil
Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia
Descriptor: Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ...
Authors:Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A.
Deposit date:2021-08-10
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
8GJA
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BU of 8gja by Molmil
RAD51C-XRCC3 structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, RAD51C, ...
Authors:Arvai, A.S, Tainer, J.A, Williams, G, Longo, M.A.
Deposit date:2023-03-15
Release date:2023-08-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.
Nat Commun, 14, 2023
8GJ9
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BU of 8gj9 by Molmil
RAD51C N-terminal domain
Descriptor: RAD51C, ZINC ION
Authors:Arvai, A.S, Tainer, J.A, Williams, G.
Deposit date:2023-03-15
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.
Nat Commun, 14, 2023
8GJ8
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BU of 8gj8 by Molmil
RAD51C C-terminal domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAD51C
Authors:Arvai, A.S, Tainer, J.A, Williams, G.
Deposit date:2023-03-15
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.
Nat Commun, 14, 2023
8GOG
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BU of 8gog by Molmil
Structure of streptavidin mutant (S112Y-K121E) complexed with biotin-cyclopentadienyl-rhodium (III)(Cp*-Rh(III))
Descriptor: CHLORIDE ION, GLYCEROL, RHODIUM(III) ION, ...
Authors:Sairaman, A, Mukherjee, P, Maiti, D, Bhaumik, P.
Deposit date:2022-08-24
Release date:2024-02-28
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Artificial metalloenzyme catalyzed enantiodivergent synthesis of isoindolones
NAT SYNTH
4OR1
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BU of 4or1 by Molmil
Structure and mechanism of fibronectin binding and biofilm formation of enteroaggregative Escherischia coli AAF fimbriae
Descriptor: ACETATE ION, Invasin homolog AafB, Major fimbrial subunit of aggregative adherence fimbria II AafA chimeric construct, ...
Authors:Lee, W.-C, Garnett, J.A, Yang, Y, Matthews, S.
Deposit date:2014-02-10
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
7TDM
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BU of 7tdm by Molmil
CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
Descriptor: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ...
Authors:Vecchio, A.J.
Deposit date:2022-01-01
Release date:2022-02-09
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
7TDN
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BU of 7tdn by Molmil
CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
Descriptor: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ...
Authors:Vecchio, A.J.
Deposit date:2022-01-01
Release date:2022-02-09
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
7PWB
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BU of 7pwb by Molmil
dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PVI
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BU of 7pvi by Molmil
dTDP-sugar epimerase
Descriptor: CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-04
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.434 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWH
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BU of 7pwh by Molmil
Structure of the dTDP-sugar epimerase StrM
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWI
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BU of 7pwi by Molmil
Structure of the dTDP-sugar epimerase StrM
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.326 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
4PHX
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BU of 4phx by Molmil
Crystal structure of AggB, the minor subunit of aggregative adherence fimbriae type I from the Escherichia coli O4H104
Descriptor: Protein AggB
Authors:Pakharukova, N.A, Tuitilla, M, Zavialov, A.V.
Deposit date:2014-05-07
Release date:2014-10-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
4PH8
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BU of 4ph8 by Molmil
Crystal structure of AggA, the major subunit of aggregative adherence fimbriae type I (AAF/I) from the Escherichia coli O4H104
Descriptor: Aggregative adherence fimbrial subunit AggA, GLYCEROL
Authors:Pakharukova, N.A, Tuitilla, M, Zavialov, A.V.
Deposit date:2014-05-05
Release date:2014-10-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
5KH0
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BU of 5kh0 by Molmil
Crystal Structure of HydF from thermosipho melanesiensis in complex with a [4Fe-4S] cluster
Descriptor: IRON/SULFUR CLUSTER, Small GTP-binding protein
Authors:Caserta, G, Pecqueur, L, Fontecave, M.
Deposit date:2016-06-14
Release date:2017-05-03
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional characterization of the hydrogenase-maturation HydF protein.
Nat. Chem. Biol., 13, 2017
5LAD
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BU of 5lad by Molmil
Crystal Structure of apo HydF from thermotoga maritima
Descriptor: Putative GTP-binding protein
Authors:Caserta, G, Pecqueur, L, Fontecave, M.
Deposit date:2016-06-14
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional characterization of the hydrogenase-maturation HydF protein.
Nat. Chem. Biol., 13, 2017
5JHQ
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BU of 5jhq by Molmil
ARCs 1-3 of human Tankyrase-1 bound to a peptide derived from IRAP
Descriptor: Peptide derived from insulin-responsive aminopeptidase (IRAP), Tankyrase-1
Authors:Eisemann, T, Pascal, J.M.
Deposit date:2016-04-21
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification.
Structure, 24, 2016
7RK8
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BU of 7rk8 by Molmil
Cryo-EM Structure of Adeno-Associated Virus Serotype 9 with Engineered Peptide Domain PHP.B (AAV9-PHP.B)
Descriptor: Capsid protein VP1
Authors:Fluck, E.C, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2021-07-22
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Context-Specific Function of the Engineered Peptide Domain of PHP.B.
J.Virol., 95, 2021
7RK9
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BU of 7rk9 by Molmil
Cryo-EM Structure of Adeno-Associated Virus Serotype 1 with Engineered Peptide Domain PHP.B (AAV1-PHP.B)
Descriptor: Capsid protein
Authors:Fluck, E.C, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2021-07-22
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.32 Å)
Cite:Context-Specific Function of the Engineered Peptide Domain of PHP.B.
J.Virol., 95, 2021
3OD8
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BU of 3od8 by Molmil
Human PARP-1 zinc finger 1 (Zn1) bound to DNA
Descriptor: 5'-D(*CP*CP*CP*AP*AP*GP*CP*GP*GP*C)-3', 5'-D(*GP*CP*CP*GP*CP*TP*TP*GP*GP*G)-3', Poly [ADP-ribose] polymerase 1, ...
Authors:Pascal, J.M, Langelier, M.-F.
Deposit date:2010-08-11
Release date:2011-01-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
3ODA
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BU of 3oda by Molmil
Human PARP-1 zinc finger 1 (Zn1) bound to DNA
Descriptor: 5'-D(*GP*CP*CP*TP*GP*CP*AP*GP*GP*C)-3', Poly [ADP-ribose] polymerase 1, ZINC ION
Authors:Pascal, J.M, Langelier, M.-F.
Deposit date:2010-08-11
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
3ODE
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BU of 3ode by Molmil
Human PARP-1 zinc finger 2 (Zn2) bound to DNA
Descriptor: 5'-D(*CP*CP*CP*AP*AP*GP*CP*G)-3', 5'-D(*CP*GP*CP*TP*TP*GP*GP*G)-3', Poly [ADP-ribose] polymerase 1, ...
Authors:Pascal, J.M, Langelier, M.-F.
Deposit date:2010-08-11
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
3ODC
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BU of 3odc by Molmil
Human PARP-1 zinc finger 2 (Zn2) bound to DNA
Descriptor: 5'-D(*CP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*G)-3', Poly [ADP-ribose] polymerase 1, ...
Authors:Pascal, J.M, Langelier, M.-F.
Deposit date:2010-08-11
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
J.Biol.Chem., 286, 2011
2ZHX
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BU of 2zhx by Molmil
Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor
Descriptor: Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor
Authors:Kaushal, P.S, Talawar, R.K, Krishna, P.D.V, Varshney, U, Vijayan, M.
Deposit date:2008-02-11
Release date:2008-05-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources
Acta Crystallogr.,Sect.D, 64, 2008

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