7RK8

Cryo-EM Structure of Adeno-Associated Virus Serotype 9 with Engineered Peptide Domain PHP.B (AAV9-PHP.B)

This is a non-PDB format compatible entry.

Summary for 7RK8

• Entry DOI: 10.2210/pdb7rk8/pdb
• EMDB information: 24494
• Descriptor: Capsid protein VP1 (1 entity in total)
• Functional Keywords: gene therapy, adeno-associated virus, aav, virus
• Biological source: Adeno-associated virus 9
• Total number of polymer chains: 60
• Total formula weight: 4932940.32

Authors

Fluck, E.C.,Pumroy, R.A.,Moiseenkova-Bell, V.Y. (deposition date: 2021-07-22, release date: 2021-08-04, Last modification date: 2021-10-06)

• Primary citation: Martino, R.A.,Fluck 3rd, E.C.,Murphy, J.,Wang, Q.,Hoff, H.,Pumroy, R.A.,Lee, C.Y.,Sims, J.J.,Roy, S.,Moiseenkova-Bell, V.Y.,Wilson, J.M.; Context-Specific Function of the Engineered Peptide Domain of PHP.B.; J.Virol., 95:e0116421-e0116421, 2021; PubMed: 34346767; DOI: 10.1128/JVI.01164-21

Experimental method

ELECTRON MICROSCOPY (2.27 Å)