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5FQ2
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BU of 5fq2 by Molmil
Crystal structure of human SUMO E1 UFD domain in complex with Ubc9 in a P422 space group.
Descriptor: SUMO-ACTIVATING ENZYME SUBUNIT 2, SUMO-CONJUGATING ENZYME UBC9
Authors:Liu, B, Castano, L, Lois, M, Reverter, D.
Deposit date:2015-12-04
Release date:2016-11-16
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Crystal Structure of Human Sumo E1 Ufd Domain in Complex with Ubc9.
To be Published
5FW8
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BU of 5fw8 by Molmil
Structure of human transthyretin mutant E89K
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW7
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BU of 5fw7 by Molmil
Structure of human transthyretin mutant A109V
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW9
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BU of 5fw9 by Molmil
Human Spectrin SH3 domain D48G, E7Y, K60Y
Descriptor: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Human Spectrin SH3 Domain D48G, E7Y, K60Y
To be Published
5FWC
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BU of 5fwc by Molmil
Human Spectrin SH3 domain D48G, E7A, K60A
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ...
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
6I6Z
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BU of 6i6z by Molmil
Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Tyr-Ala-Y(PO2CH2)-homoPhe-OH
Descriptor: (2S)-2-{[(S)-{(1R)-1-[(N-acetyl-L-tyrosyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, Carboxypeptidase A1, ZINC ION
Authors:Gallego, P, Reverter, D.
Deposit date:2018-11-15
Release date:2018-12-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes.
J. Med. Chem., 62, 2019
3ZKF
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BU of 3zkf by Molmil
Structure of LC8 in complex with Nek9 phosphopeptide
Descriptor: DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN
Authors:Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D.
Deposit date:2013-01-22
Release date:2013-03-20
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
6FWW
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BU of 6fww by Molmil
GFP/KKK. A redesigned GFP with improved solubility
Descriptor: Green fluorescent protein
Authors:Varejao, N, Lascorz, J, Gil-Garcia, M, Diaz-Caballero, M, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2018-03-07
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.131 Å)
Cite:Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.
Mol. Pharm., 15, 2018
6FXU
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BU of 6fxu by Molmil
Crystal structure of human transthyretin mutant T119M at pH 5.5
Descriptor: Transthyretin
Authors:Varejao, N, Esperante, S, Ventura, S, Reverter, D.
Deposit date:2018-03-09
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.359 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FZL
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BU of 6fzl by Molmil
Crystal structure of human transthyretin double mutant K35T/T119M
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-15
Release date:2019-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.446 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FWD
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BU of 6fwd by Molmil
Crystal structure of human transthyretin double mutant R34G/T119M at pH 5.5
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-06
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6GUM
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BU of 6gum by Molmil
Structure of the A.thaliana E1 UFD domain in complex with E2
Descriptor: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1
Authors:Liu, B, Lois, L.M, Reverter, D.
Deposit date:2018-06-19
Release date:2019-07-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
6GV3
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BU of 6gv3 by Molmil
Structure of the E2 conjugating enzyme, SCE1, from Arabidopsis thaliana.
Descriptor: SUMO-conjugating enzyme SCE1
Authors:Liu, B, Lois, L.M, Reverter, D.
Deposit date:2018-06-20
Release date:2019-07-03
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (1.201 Å)
Cite:Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
3ZKE
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BU of 3zke by Molmil
Structure of LC8 in complex with Nek9 peptide
Descriptor: DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN
Authors:Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D.
Deposit date:2013-01-22
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
3ZO5
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BU of 3zo5 by Molmil
Structure of SENP2-Loop1 in complex with preSUMO-2
Descriptor: SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 2
Authors:Alegre, K.O, Reverter, D.
Deposit date:2013-02-20
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Insights Into the Senp6 Loop1 Structure in Complex with Sumo2.
Protein Sci., 23, 2014
4A37
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BU of 4a37 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa
Descriptor: METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4A39
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BU of 4a39 by Molmil
Metallo-carboxypeptidase from Pseudomonas Aeruginosa in complex with (2-guanidinoethylmercapto)succinic acid
Descriptor: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4AMU
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BU of 4amu by Molmil
Structure of ornithine carbamoyltransferase from Mycoplasma penetrans with a P321 space group
Descriptor: ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
Authors:Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D.
Deposit date:2012-03-13
Release date:2012-03-28
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
4A38
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BU of 4a38 by Molmil
METALLO-CARBOXYPEPTIDASE FROM PSEUDOMONAS AUREGINOSA IN COMPLEX WITH L-BENZYLSUCCINIC ACID
Descriptor: L-BENZYLSUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION
Authors:Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D.
Deposit date:2011-09-30
Release date:2012-05-09
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Faseb J., 26, 2012
4ANF
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BU of 4anf by Molmil
Structure of the ornithine carbamoyltransferase from Mycoplasma penetrans with a P23 Space group
Descriptor: ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
Authors:Gallego, P, Benach, J, Planell, R, Querol, E, Perez-Pons, J.A, Reverter, D.
Deposit date:2012-03-16
Release date:2012-03-28
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
4A94
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BU of 4a94 by Molmil
Structure of the carboxypeptidase inhibitor from Nerita versicolor in complex with human CPA4
Descriptor: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR, NITRATE ION, ...
Authors:Covaleda, G, Alonso, M, Chavez, M.A, Aviles, F.X, Reverter, D.
Deposit date:2011-11-23
Release date:2011-12-28
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of a Novel Metallo-Carboxypeptidase Inhibitor from the Marine Mollusk Nerita Versicolor in Complex with Human Carboxypeptidase A4.
J.Biol.Chem., 287, 2012
4AXS
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BU of 4axs by Molmil
Structure of Carbamate Kinase from Mycoplasma penetrans
Descriptor: CARBAMATE KINASE, SULFATE ION
Authors:Gallego, P, Planell, R, Benach, J, Querol, E, PerezPons, J.A, Reverter, D.
Deposit date:2012-06-14
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma Penetrans.
Plos One, 7, 2012
4BD9
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BU of 4bd9 by Molmil
Structure of the complex between SmCI and human carboxypeptidase A4
Descriptor: CARBOXYPEPTIDASE A4, CARBOXYPEPTIDASE INHIBITOR SMCI, ZINC ION
Authors:Alonso-del-Ribero, M, Reytor, M.L, Trejo, S.A, Chavez, M.A, Aviles, F.X, Reverter, D.
Deposit date:2012-10-05
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz Smci in Complex with Human Cpa4.
Structure, 21, 2013
4E4J
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BU of 4e4j by Molmil
Crystal structure of arginine deiminase from Mycoplasma penetrans
Descriptor: Arginine deiminase, CHLORIDE ION
Authors:Benach, J, Gallego, P, Planell, R, Querol, E, Perez Pons, J.A, Reverter, D.
Deposit date:2012-03-13
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma penetrans.
Plos One, 7, 2012
1KFX
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BU of 1kfx by Molmil
Crystal Structure of Human m-Calpain Form I
Descriptor: M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
Authors:Strobl, S, Fernandez-Catalan, C, Braun, M, Huber, R, Masumoto, H, Nakagawa, K, Irie, A, Sorimachi, H, Bourenkow, G, Bartunik, H, Suzuki, K, Bode, W.
Deposit date:2001-11-23
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000

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