6R83
 
 | | CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH) | | Descriptor: | Hemocyanin subunit 1 | | Authors: | Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C. | | Deposit date: | 2019-03-31 | | Release date: | 2019-05-08 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Cryo-EM reveals the asymmetric assembly of squid hemocyanin.
Iucrj, 6, 2019
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6T24
 | | Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) | | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Pospich, S, Merino, F, Raunser, S. | | Deposit date: | 2019-10-07 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments.
Structure, 28, 2020
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6T20
 | | Cryo-EM structure of phalloidin-stabilized F-actin (aged) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Merino, F, Raunser, S. | | Deposit date: | 2019-10-07 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments.
Structure, 28, 2020
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6T1Y
 | | Cryo-EM structure of phalloidin-stabilized F-actin (copolymerized) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Merino, F, Raunser, S. | | Deposit date: | 2019-10-07 | | Release date: | 2020-03-04 | | Last modified: | 2020-04-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments.
Structure, 28, 2020
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7QPG
 | | Human RZZ kinetochore corona complex. | | Descriptor: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | | Authors: | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | | Deposit date: | 2022-01-04 | | Release date: | 2022-03-16 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores.
Embo J., 41, 2022
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7B16
 | | TRPC4 in complex with inhibitor GFB-9289 | | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-23 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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7B0S
 | | TRPC4 in complex with inhibitor GFB-8438 | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-21 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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7B0J
 | | TRPC4 in LMNG detergent | | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, Transient receptor potential cation channel subfamily c member 4a | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-20 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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7B1G
 | | TRPC4 in complex with Calmodulin | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-24 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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7B05
 | | TRPC4 in complex with inhibitor GFB-8749 | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-18 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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6ZXK
 | | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement | | Descriptor: | Lethal factor, Protective antigen | | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | | Deposit date: | 2020-07-29 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
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6ZXL
 | | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement | | Descriptor: | Lethal factor, Protective antigen | | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | | Deposit date: | 2020-07-29 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
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7AD9
 | | Structure of the Lifeact-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Belyy, A, Merino, F, Sitsel, O, Raunser, S. | | Deposit date: | 2020-09-14 | | Release date: | 2020-10-28 | | Last modified: | 2020-12-02 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of the Lifeact-F-actin complex.
Plos Biol., 18, 2020
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6ZXJ
 | | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked) | | Descriptor: | Lethal factor, Protective antigen | | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | | Deposit date: | 2020-07-29 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
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8S3E
 | | Structure of rabbit Slo1 in complex with gamma1/LRRC26 | | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | | Authors: | Redhardt, M, Raunser, S, Raisch, T. | | Deposit date: | 2024-02-20 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.39 Å) | | Cite: | Cryo-EM structure of the Slo1 potassium channel with the auxiliary gamma 1 subunit suggests a mechanism for depolarization-independent activation.
Febs Lett., 598, 2024
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7Q5P
 | | Structure of VgrG1 from Pseudomonas protegens. | | Descriptor: | Type VI secretion protein VgrG | | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | | Deposit date: | 2021-11-04 | | Release date: | 2021-12-15 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system.
Plos Pathog., 18, 2022
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7Q97
 | | Structure of the bacterial type VI secretion system effector RhsA. | | Descriptor: | Rhs family protein | | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | | Deposit date: | 2021-11-12 | | Release date: | 2021-12-22 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system.
Plos Pathog., 18, 2022
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7QLA
 | | Structure of the Rab GEF complex Mon1-Ccz1 | | Descriptor: | Ccz1, Vacuolar fusion protein MON1 | | Authors: | Klink, B.U, Herrmann, E, Antoni, C, Langemeyer, L, Kiontke, S, Gatsogiannis, C, Ungermann, C, Raunser, S, Kuemmel, D. | | Deposit date: | 2021-12-20 | | Release date: | 2022-02-09 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7QIO
 | | Homology model of myosin neck domain in skeletal sarcomere | | Descriptor: | Myosin light chain 1/3, skeletal muscle isoform, Myosin regulatory light chain 2, ... | | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | Deposit date: | 2021-12-15 | | Release date: | 2022-02-16 | | Last modified: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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7QIN
 | | In situ structure of actomyosin complex in skeletal sarcomere | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | Deposit date: | 2021-12-15 | | Release date: | 2022-02-16 | | Last modified: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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7QIM
 | | In situ structure of nebulin bound to actin filament in skeletal sarcomere | | Descriptor: | ACTS protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | Deposit date: | 2021-12-15 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.
Science, 375, 2022
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7ZBQ
 | | Structure of the ADP-ribosyltransferase TccC3HVR from Photorhabdus Luminescens | | Descriptor: | TccC3 | | Authors: | Lindemann, F, Belyy, A, Friedrich, D, Schmieder, P, Bardiaux, B, Roderer, D, Funk, J, Protze, J, Bieling, P, Oschkinat, H, Raunser, S. | | Deposit date: | 2022-03-24 | | Release date: | 2022-06-29 | | Last modified: | 2022-08-03 | | Method: | SOLUTION NMR | | Cite: | Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Nat Commun, 13, 2022
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6RWA
 | | Cryo-EM structure of Photorhabdus luminescens TcdA4 | | Descriptor: | TcdA4 | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6RW6
 | | Cryo-EM structure of Photorhabdus luminescens TcdA1 | | Descriptor: | TcdA1 | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6SFW
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