3J8F
 
 | | Cryo-EM reconstruction of poliovirus-receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, ... | | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | | Deposit date: | 2014-10-20 | | Release date: | 2015-02-11 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry.
J.Virol., 89, 2015
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4O8J
 | | Crystal structure of RtcA, the RNA 3'-terminal phosphate cyclase from Pyrococcus horikoshii, in complex with rACAAA3'phosphate and adenine. | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE, RNA, ... | | Authors: | Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. | | Deposit date: | 2013-12-27 | | Release date: | 2014-09-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structure of RNA 3'-phosphate cyclase bound to substrate RNA.
Rna, 20, 2014
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8E8Q
 | | Cryo-EM structure of substrate-free DNClpX.ClpP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-08-25 | | Release date: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structure of substrate-free DNClpX.ClpP
Nat Commun, 2023
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8E7V
 | | Cryo-EM structure of substrate-free DNClpX.ClpP from singly capped particles | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-08-24 | | Release date: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of substrate-free DNClpX.ClpP
Nat Commun, 2023
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8E91
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8ET3
 | | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Ghanbarpour, A, Fei, X, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-10-16 | | Release date: | 2023-01-25 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8ESX
 | | HIV protease in complex with benzoxaborolone analog of darunavir | | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Windsor, I.W, Graham, B.J, Raines, R.T. | | Deposit date: | 2022-10-15 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability.
Acs Med.Chem.Lett., 14, 2023
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3J9F
 | | Poliovirus complexed with soluble, deglycosylated poliovirus receptor (Pvr) at 4 degrees C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | | Deposit date: | 2015-01-15 | | Release date: | 2015-02-11 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry.
J.Virol., 89, 2015
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4OQU
 | | Structure of the SAM-I/IV riboswitch (env87(deltaU92)) | | Descriptor: | MAGNESIUM ION, S-ADENOSYLMETHIONINE, SAM-I/IV riboswitch | | Authors: | Trausch, J.J, Reyes, F.E, Edwards, A.L, Batey, R.T. | | Deposit date: | 2014-02-10 | | Release date: | 2014-06-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for diversity in the SAM clan of riboswitches.
Proc.Natl.Acad.Sci.USA, 111, 2014
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8ESY
 | | D30N mutant HIV protease in complex with benzoxaborolone analog of darunavir | | Descriptor: | CHLORIDE ION, GLYCEROL, Protease, ... | | Authors: | Windsor, I.W, Graham, B.J, Raines, R.T. | | Deposit date: | 2022-10-15 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability.
Acs Med.Chem.Lett., 14, 2023
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4O89
 | | Crystal structure of RtcA, the RNA 3'-terminal phosphate cyclase from Pyrococcus horikoshii. | | Descriptor: | CITRIC ACID, RNA 3'-terminal phosphate cyclase | | Authors: | Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. | | Deposit date: | 2013-12-26 | | Release date: | 2014-09-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of RNA 3'-phosphate cyclase bound to substrate RNA.
Rna, 20, 2014
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3K0X
 | | Crystal structure of telomere capping protein Ten1 from Saccharomyces pombe | | Descriptor: | IODIDE ION, Protein Ten1 | | Authors: | Gelinas, A.D, Reyes, F.E, Batey, R.T, Wuttke, D.S. | | Deposit date: | 2009-09-25 | | Release date: | 2009-10-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4OJR
 | | Crystal Structure of the HIV-1 Integrase catalytic domain with GSK1264 | | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, CACODYLATE ION, HIV-1 Integrase, ... | | Authors: | Gupta, K, Brady, T, Dyer, B, Hwang, Y, Male, F, Nolte, R.T, Wang, L, Velthuisen, E, Jeffrey, J, Van Duyne, G, Bushman, F.D. | | Deposit date: | 2014-01-21 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS.
J.Biol.Chem., 289, 2014
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3KB7
 | | Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor | | Descriptor: | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ... | | Authors: | Bossi, R.T, Bertrand, J.A. | | Deposit date: | 2009-10-20 | | Release date: | 2010-05-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors
J.Med.Chem., 53, 2010
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3L0U
 | | The crystal structure of unmodified tRNAPhe from Escherichia coli | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, Unmodified tRNAPhe | | Authors: | Byrne, R.T, Konevega, A.L, Rodnina, M.V, Antson, A.A. | | Deposit date: | 2009-12-10 | | Release date: | 2010-03-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure of unmodified tRNAPhe from Escherichia coli
Nucleic Acids Res., 38, 2010
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4PER
 | | Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I | | Descriptor: | Angiogenin, Ribonuclease Inhibitor | | Authors: | Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G. | | Deposit date: | 2014-04-24 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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4PEQ
 | | Structure of bovine ribonuclease inhibitor complexed with bovine ribonuclease I | | Descriptor: | Ribonuclease pancreatic, Ribonuclease/angiogenin inhibitor 1 | | Authors: | Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G. | | Deposit date: | 2014-04-24 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.211 Å) | | Cite: | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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3LH1
 | | Q191A mutant of the DegS-deltaPDZ | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.507 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGU
 | | Y162A mutant of the DegS-deltaPDZ protease | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGY
 | | R178A mutant of the DegS-deltaPDZ protease | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LQX
 | | SRP ribonucleoprotein core complexed with cobalt hexammine | | Descriptor: | CHLORIDE ION, COBALT HEXAMMINE(III), POTASSIUM ION, ... | | Authors: | Batey, R.T. | | Deposit date: | 2010-02-10 | | Release date: | 2010-03-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural and Energetic Analysis of Metal Ions Essential to SRP Signal Recognition Domain Assembly
Biochemistry, 41, 2002
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3LGV
 | | H198P mutant of the DegS-deltaPDZ protease | | Descriptor: | Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.734 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
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3LGW
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3LGI
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3LGT
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