1AER
| DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD | 分子名称: | 2-(1,5-DIDEOXYRIBOSE)-4-AMIDO-THIAZOLE, ADENOSINE MONOPHOSPHATE, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... | 著者 | Li, M, Dyda, F, Benhar, I, Pastan, I, Davies, D.R. | 登録日 | 1995-12-11 | 公開日 | 1996-06-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation Proc.Natl.Acad.Sci.USA, 93, 1996
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1DMA
| DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH NICOTINAMIDE AND AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, EXOTOXIN A, NICOTINAMIDE | 著者 | Li, M, Dyda, F, Benhar, I, Pastan, I, Davies, D. | 登録日 | 1995-04-28 | 公開日 | 1995-09-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. Proc.Natl.Acad.Sci.USA, 92, 1995
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4F3F
| Crystal Structure of Msln7-64 MORAb-009 FAB complex | 分子名称: | MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin | 著者 | Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L. | 登録日 | 2012-05-09 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights. J.Biol.Chem., 287, 2012
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1DSF
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8CX3
| Crystal structure of full-length mesothelin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Zhan, J, Esser, L, Xia, D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.609 Å) | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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7U8C
| Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex | 分子名称: | MORab 15B6 Fab heavy chain, MORab 15B6 Fab light chain, Mesothelin, ... | 著者 | Zhan, J, Esser, L, Xia, D. | 登録日 | 2022-03-08 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin. Proc.Natl.Acad.Sci.USA, 119, 2022
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7UED
| Crystal structure of full length mesothelin bound with MORAb-009 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Isoform 4 of Mesothelin, ... | 著者 | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | 登録日 | 2022-03-21 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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7U9J
| Crystal structure of Mesothelin-207 fragment | 分子名称: | GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION | 著者 | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | 登録日 | 2022-03-10 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3, 2023
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4F33
| Crystal Structure of therapeutic antibody MORAb-009 | 分子名称: | MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL | 著者 | Xia, D, Ma, J, Tang, W.K, Esser, L. | 登録日 | 2012-05-08 | 公開日 | 2012-07-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | 主引用文献 | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights. J.Biol.Chem., 287, 2012
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1IKP
| Pseudomonas Aeruginosa Exotoxin A, P201Q, W281A mutant | 分子名称: | CHLORIDE ION, EXOTOXIN A, SODIUM ION | 著者 | McKay, D.B, Wedekind, J.E, Trame, C.B. | 登録日 | 2001-05-04 | 公開日 | 2001-12-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Refined Crystallographic Structure of Pseudomonas aeruginosa Exotoxin A
and its Implications for the Molecular Mechanism of Toxicity J.Mol.Biol., 314, 2001
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1IKQ
| Pseudomonas Aeruginosa Exotoxin A, wild type | 分子名称: | CHLORIDE ION, EXOTOXIN A, SODIUM ION | 著者 | McKay, D.B, Wedekind, J.E, Trame, C.B. | 登録日 | 2001-05-04 | 公開日 | 2001-12-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Refined Crystallographic Structure of Pseudomonas aeruginosa Exotoxin A
and its Implications for the Molecular Mechanism of Toxicity J.Mol.Biol., 314, 2001
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