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8A2Q
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BU of 8a2q by Molmil
Structure of the DNA-bound FANCD2-FANCI complex containing phosphomimetic FANCI
分子名称: DNA (29-MER), FANCD2, Fanconi anemia complementation group I
著者Passmore, L.A, Sijacki, T, Alcon, P.
登録日2022-06-06
公開日2022-09-07
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination.
Nat.Struct.Mol.Biol., 29, 2022
4V1W
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BU of 4v1w by Molmil
3D structure of horse spleen apoferritin determined by electron cryomicroscopy
分子名称: FERRITIN LIGHT CHAIN
著者Russo, C.J, Passmore, L.A.
登録日2014-10-02
公開日2014-12-10
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Electron Microscopy. Ultrastable Gold Substrates for Electron Cryomicroscopy.
Science, 346, 2014
7ZGR
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BU of 7zgr by Molmil
Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA
分子名称: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ...
著者Rodriguez-Molina, J.B, Passmore, L.A.
登録日2022-04-04
公開日2022-05-25
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGP
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BU of 7zgp by Molmil
Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA
分子名称: MPE1 isoform 1, Polyadenylation factor subunit 2, Protein CFT1, ...
著者Rodriguez-Molina, J.B, Passmore, L.A.
登録日2022-04-04
公開日2022-05-25
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGQ
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BU of 7zgq by Molmil
Polymerase module of yeast CPF in complex with the yPIM of Cft2
分子名称: Cleavage factor two protein 2, Polyadenylation factor subunit 2, Protein CFT1, ...
著者Rodriguez-Molina, J.B, Passmore, L.A.
登録日2022-04-04
公開日2022-05-25
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
8A8F
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BU of 8a8f by Molmil
Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
分子名称: MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ...
著者Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A.
登録日2022-06-22
公開日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
To Be Published
8BPO
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BU of 8bpo by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S.
登録日2022-11-17
公開日2023-07-05
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol.Cell, 83, 2023
6I1D
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BU of 6i1d by Molmil
Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae
分子名称: Endoribonuclease YSH1, GLYCEROL, Protein MPE1, ...
著者Hill, C.H, Boreikaite, V, Kumar, A, Casanal, A, Kubik, P, Degliesposti, G, Maslen, S, Mariani, A, von Loeffelholz, O, Girbig, M, Skehel, M, Passmore, L.A.
登録日2018-10-28
公開日2019-02-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.
Mol.Cell, 73, 2019
4CYJ
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BU of 4cyj by Molmil
Chaetomium thermophilum Pan2:Pan3 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
著者Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
登録日2014-04-11
公開日2014-06-11
最終更新日2014-07-30
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
著者Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
登録日2014-04-11
公開日2014-06-11
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYK
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BU of 4cyk by Molmil
Structural basis for binding of Pan3 to Pan2 and its function in mRNA recruitment and deadenylation
分子名称: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, ZINC ION
著者Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
登録日2014-04-11
公開日2014-05-21
最終更新日2021-06-23
実験手法SOLUTION NMR
主引用文献Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation.
Embo J., 33, 2014
6FPP
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BU of 6fpp by Molmil
Structure of S. pombe Mmi1
分子名称: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
著者Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
登録日2018-02-11
公開日2018-05-09
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPQ
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BU of 6fpq by Molmil
Structure of S. pombe Mmi1 in complex with 7-mer RNA
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
著者Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
登録日2018-02-11
公開日2018-05-09
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPX
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BU of 6fpx by Molmil
Structure of S. pombe Mmi1 in complex with 11-mer RNA
分子名称: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1
著者Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
登録日2018-02-12
公開日2018-05-09
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6R9J
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BU of 6r9j by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with A7 RNA
分子名称: A7 RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.326 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9P
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BU of 6r9p by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAUUAA RNA
分子名称: AAUUAA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9O
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BU of 6r9o by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAGGA RNA
分子名称: AAGGA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.319 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9I
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BU of 6r9i by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module
分子名称: PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9M
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BU of 6r9m by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAGGAA RNA
分子名称: AAGGAA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.329 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9Q
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BU of 6r9q by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AACCAA RNA
分子名称: AACCAA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.079 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6SRS
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BU of 6srs by Molmil
Structure of the Fanconi anaemia core subcomplex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6SRI
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BU of 6sri by Molmil
Structure of the Fanconi anaemia core complex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6TNG
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BU of 6tng by Molmil
Structure of FANCD2 in complex with FANCI
分子名称: Fanconi anemia complementation group I, Uncharacterized protein
著者Alcon, P, Shakeel, S, Passmore, L.A.
登録日2019-12-07
公開日2020-02-19
最終更新日2020-03-18
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6TNF
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BU of 6tnf by Molmil
Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA
分子名称: DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ...
著者Alcon, P, Shakeel, S, Passmore, L.A.
登録日2019-12-07
公開日2020-02-19
最終更新日2020-03-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6TNI
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BU of 6tni by Molmil
Structure of FANCD2 homodimer
分子名称: Uncharacterized protein
著者Alcon, P, Shakeel, S, Passmore, L.A.
登録日2019-12-08
公開日2020-02-19
最終更新日2020-03-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020

 

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