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6H08
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BU of 6h08 by Molmil
The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with a His175Me-His proximal ligand substitution
分子名称: COBALT (II) ION, Cytochrome c peroxidase, mitochondrial, ...
著者Ortmayer, M, Levy, C, Green, A.P.
登録日2018-07-06
公開日2020-02-12
最終更新日2020-07-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rewiring the "Push-Pull" Catalytic Machinery of a Heme Enzyme Using an Expanded Genetic Code.
Acs Catalysis, 10, 2020
6Y2Y
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BU of 6y2y by Molmil
The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with Trp51 to S-Trp51 and Trp191Phe modifications
分子名称: 1,2-ETHANEDIOL, Cytochrome c peroxidase, mitochondrial, ...
著者Ortmayer, M, Levy, C, Green, A.P.
登録日2020-02-17
公開日2021-06-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase.
Jacs Au, 1, 2021
6Y1T
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BU of 6y1t by Molmil
The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with a Trp51 to S-Trp51 modification
分子名称: 1,2-ETHANEDIOL, Cytochrome c peroxidase, mitochondrial, ...
著者Ortmayer, M, Levy, C, Green, A.P.
登録日2020-02-13
公開日2021-06-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase.
Jacs Au, 1, 2021
5LTE
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BU of 5lte by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM)
分子名称: 2-ETHOXYETHANOL, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
著者Ortmayer, M, Leys, D.
登録日2016-09-06
公開日2016-11-09
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTI
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BU of 5lti by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate
分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYLAMINE, NITRIC OXIDE, ...
著者Ortmayer, M, Leys, D.
登録日2016-09-06
公開日2016-11-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTH
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BU of 5lth by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate
分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYLAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ortmayer, M, Leys, D.
登録日2016-09-06
公開日2016-11-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
8C3W
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BU of 8c3w by Molmil
Crystal structure of a computationally designed heme binding protein, dnHEM1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
著者Ortmayer, M, Levy, C.
登録日2022-12-29
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site.
J.Am.Chem.Soc., 145, 2023
5A3C
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BU of 5a3c by Molmil
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with NAD
分子名称: 1,2-ETHANEDIOL, GLYCINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I.
登録日2015-05-28
公開日2015-07-29
最終更新日2015-10-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A3B
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BU of 5a3b by Molmil
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with ADP-ribose
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, ALANINE, ...
著者Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I.
登録日2015-05-28
公開日2015-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A3A
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BU of 5a3a by Molmil
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes (Apo form)
分子名称: 1,2-ETHANEDIOL, GLYCINE, SIR2 FAMILY PROTEIN, ...
著者Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I.
登録日2015-05-28
公開日2015-07-29
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A35
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BU of 5a35 by Molmil
Crystal structure of Glycine Cleavage Protein H-Like (GcvH-L) from Streptococcus pyogenes
分子名称: GLYCINE CLEAVAGE SYSTEM H PROTEIN, PENTAETHYLENE GLYCOL
著者Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I.
登録日2015-05-27
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
6Q7Q
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BU of 6q7q by Molmil
Crystal structure of OE1.3
分子名称: OE1.3
著者Levy, C.W.
登録日2018-12-13
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7P
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BU of 6q7p by Molmil
Crystal structure of OE1.2
分子名称: 1,2-ETHANEDIOL, 1-PHENYLETHANONE, MAGNESIUM ION, ...
著者Levy, C.W.
登録日2018-12-13
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7R
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BU of 6q7r by Molmil
Crystal structure of OE1.3 alkylated with the mechanistic inhibitor 2-bromoacetophenone
分子名称: 1-PHENYLETHANONE, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Levy, C.W.
登録日2018-12-13
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7O
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BU of 6q7o by Molmil
Crystal structure of OE1
分子名称: CALCIUM ION, OE1
著者Levy, C.W.
登録日2018-12-13
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7N
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BU of 6q7n by Molmil
Crystal structure of BH32 alkylated with the mechanistic inhibitor 2-bromoacetophenone
分子名称: 1-PHENYLETHANONE, BH32
著者Levy, C.W.
登録日2018-12-13
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019

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件を2024-04-24に公開中

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