1MAZ
| X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH | 分子名称: | Bcl-2-like protein 1 | 著者 | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | 登録日 | 1996-04-09 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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4ATO
| New insights into the mechanism of bacterial Type III toxin-antitoxin systems: selective toxin inhibition by a non-coding RNA pseudoknot | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, TOXI, TOXN | 著者 | Short, F.L, Pei, X.Y, Blower, T.R, Ong, S.L, Luisi, B.F, Salmond, G.P.C. | 登録日 | 2012-05-09 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Selectivity and Self-Assembly in the Control of a Bacterial Toxin by an Antitoxic Noncoding RNA Pseudoknot. Proc.Natl.Acad.Sci.USA, 110, 2013
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8BLT
| Structure of Lactobacillus salivarius (Ls) bile salt hydrolase(BSH) in complex with taurocholate (TCA) | 分子名称: | Bile salt hydrolase, TAUROCHOLIC ACID | 著者 | Karlov, D.S, Long, S.L, Zeng, X, Xu, F, Lal, K, Cao, L, Hayoun, K, Lin, J, Joyce, S.A, Tikhonova, I.G. | 登録日 | 2022-11-10 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses. Structure, 31, 2023
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8BLS
| Structure of Lactobacillus salivarius (Ls) bile salt hydrolase(BSH) in complex with Glycocholate (GCA) | 分子名称: | Bile salt hydrolase, GLYCOCHOLIC ACID | 著者 | Karlov, D.S, Long, S.L, Zeng, X, Xu, F, Lal, K, Cao, L, Hayoun, K, Lin, J, Joyce, S.A, Tikhonova, I.G. | 登録日 | 2022-11-10 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses. Structure, 31, 2023
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6VJK
| Streptavidin mutant M88 (N49C/A86C) | 分子名称: | BIOTIN, Streptavidin | 著者 | Marangoni, J.M, Wu, S.C, Fogen, D, Wong, S.L, Ng, K.K.S. | 登録日 | 2020-01-16 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Engineering a disulfide-gated switch in streptavidin enables reversible binding without sacrificing binding affinity. Sci Rep, 10, 2020
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6VJL
| Streptavidin mutant M112 (G26C/A46C) | 分子名称: | BIOTIN, Streptavidin | 著者 | Marangoni, J.M, Wu, S.C, Fogen, D, Wong, S.L, Ng, K.K.S. | 登録日 | 2020-01-16 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Engineering a disulfide-gated switch in streptavidin enables reversible binding without sacrificing binding affinity. Sci Rep, 10, 2020
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4JO6
| Streptavidin complex with SBP-Tag | 分子名称: | SBP-Tag, Streptavidin | 著者 | Barrette-Ng, I.H, Wu, S.C, Tjia, W.M, Wong, S.L, Ng, K.K.S. | 登録日 | 2013-03-17 | 公開日 | 2013-05-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The structure of the SBP-Tag-streptavidin complex reveals a novel helical scaffold bridging binding pockets on separate subunits Acta Crystallogr.,Sect.D, 69, 2013
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1LXL
| NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BCL-XL | 著者 | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | 登録日 | 1996-04-04 | 公開日 | 1997-04-21 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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1OS8
| RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN | 分子名称: | CALCIUM ION, SULFATE ION, trypsin | 著者 | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | 登録日 | 2003-03-18 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin. Biochemistry, 42, 2003
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1OSS
| T190P STREPTOMYCES GRISEUS TRYPSIN IN COMPLEX WITH BENZAMIDINE | 分子名称: | BENZAMIDINE, CALCIUM ION, SULFATE ION, ... | 著者 | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | 登録日 | 2003-03-20 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin. Biochemistry, 42, 2003
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4EKV
| Streptavidin 8-aa-loop H127C mutein with reversible biotin binding | 分子名称: | BIOTIN, CHLORIDE ION, Streptavidin | 著者 | Barrette-Ng, I.H, Honetschlaeger, C, Wong, S.L, Ng, K.K.S. | 登録日 | 2012-04-09 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of a tetrameric streptavidin mutein with reversible biotin binding capability: engineering a mobile loop as an exit door for biotin. Plos One, 7, 2012
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2KZT
| Structure of the Tandem MA-3 Region of Pdcd4 | 分子名称: | Programmed cell death protein 4 | 著者 | Waters, L.C, Strong, S.L, Oka, O, Muskett, F.W, Veverka, V, Banerjee, S, Schmedt, T, Henry, A.J, Klempnauer, K.H, Carr, M.D. | 登録日 | 2010-06-24 | 公開日 | 2011-03-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor J.Biol.Chem., 286, 2011
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7UI0
| Post-fusion ectodomain of HSV-1 gB in complex with HSV010-13 Fab | 分子名称: | Envelope glycoprotein B, HSV10-13 Fab Heavy chain, HSV10-13 Light chain | 著者 | Windsor, I.W, Kong, S.L, Garforth, S.J, Almo, S.C, Harrison, S.C. | 登録日 | 2022-03-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice. J.Clin.Invest., 133, 2023
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7UHZ
| Post-fusion ectodomain of HSV-1 gB in complex with BMPC-23 Fab | 分子名称: | BMPC-23 Fab Heavy chain, BMPC-23 Fab Light chain, Envelope glycoprotein B | 著者 | Windsor, I.W, Kong, S.L, Garforth, S.J, Almo, S.C, Harrison, S.C. | 登録日 | 2022-03-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice. J.Clin.Invest., 133, 2023
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2M05
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2FMJ
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6KRG
| Crystal structure of sfGFP Y182TMSiPhe | 分子名称: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | 著者 | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | 登録日 | 2019-08-21 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe. Nat Commun, 11, 2020
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8CDG
| Crystal structure of human IL-17A cytokine in complex with macrocycle | 分子名称: | (9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl-2-(2-phenylethanoylamino)ethanoyl]amino]phenyl]methyl]-12-methyl-7,10,13,21-tetrakis(oxidanylidene)-8,11,14,20-tetrazaspiro[4.17]docosane-19-carboxylic acid, Interleukin-17A | 著者 | Schulze, M.-S. | 登録日 | 2023-01-30 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism. Chem Sci, 14, 2023
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7CKG
| Crystal structure of TMSiPheRS complexed with TMSiPhe | 分子名称: | 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase | 著者 | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | 登録日 | 2020-07-17 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe. Nat Commun, 11, 2020
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7CKH
| Crystal structure of TMSiPheRS | 分子名称: | Tyrosine--tRNA ligase | 著者 | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | 登録日 | 2020-07-17 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.79492676 Å) | 主引用文献 | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe. Nat Commun, 11, 2020
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3E17
| Crystal structure of the second PDZ domain from human Zona Occludens-2 | 分子名称: | Tight junction protein ZO-2 | 著者 | Chen, H, Tong, S.L, Teng, M.K, Niu, L.W. | 登録日 | 2008-08-01 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the second PDZ domain from human zonula occludens 2 Acta Crystallogr.,Sect.F, 65, 2009
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5O57
| Solution Structure of the N-terminal Region of Dkk4 | 分子名称: | Dickkopf-related protein 4 | 著者 | Waters, L.C, Patel, S, Barkell, A.M, Muskett, F.W, Robinson, M.K, Holdsworth, G, Carr, M.D. | 登録日 | 2017-06-01 | 公開日 | 2018-06-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins. J. Biol. Chem., 293, 2018
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