2KZT

Structure of the Tandem MA-3 Region of Pdcd4

Summary for 2KZT

• Entry DOI: 10.2210/pdb2kzt/pdb
• Descriptor: Programmed cell death protein 4 (2 entities in total)
• Functional Keywords: pdcd4, ma-3, eif4a, heat, apoptosis
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q53EL6 Q61823
• Total number of polymer chains: 2
• Total formula weight: 32746.54

Authors

Waters, L.C.,Strong, S.L.,Oka, O.,Muskett, F.W.,Veverka, V.,Banerjee, S.,Schmedt, T.,Henry, A.J.,Klempnauer, K.H.,Carr, M.D. (deposition date: 2010-06-24, release date: 2011-03-16, Last modification date: 2011-11-23)

• Primary citation: Waters, L.C.,Strong, S.L.,Ferlemann, E.,Oka, O.,Muskett, F.W.,Veverka, V.,Banerjee, S.,Schmedt, T.,Henry, A.J.,Klempnauer, K.H.,Carr, M.D.; Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor; J.Biol.Chem., 286:17270-17280, 2011; PubMed: 21454508; DOI: 10.1074/jbc.M110.166157

Experimental method

SOLUTION NMR