2EQB
| Crystal structure of the Rab GTPase Sec4p, the Sec2p GEF domain, and phosphate complex | Descriptor: | PHOSPHATE ION, Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4 | Authors: | Sato, Y, Fukai, S, Ishitani, R, Nureki, O. | Deposit date: | 2007-03-30 | Release date: | 2007-05-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Sec4p{middle dot}Sec2p complex in the nucleotide exchanging intermediate state Proc.Natl.Acad.Sci.Usa, 104, 2007
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6IS6
| Crystal structure of Thermoplasmatales archaeon heliorhodopsin | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, RETINAL, heliorhodopsin | Authors: | Shihoya, W, Yamashita, K, Nureki, O. | Deposit date: | 2018-11-15 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of heliorhodopsin. Nature, 574, 2019
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7V6C
| Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | Descriptor: | Dicer-2, isoform A, R2D2, ... | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V6B
| Structure of the Dicer-2-R2D2 heterodimer | Descriptor: | Dicer-2, isoform A, R2D2 | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V93
| Cryo-EM structure of the Cas12c2-sgRNA binary complex | Descriptor: | cas12c2, sgRNA | Authors: | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-24 | Release date: | 2022-04-13 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
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7V73
| Thermostabilized human prestin in complex with chloride | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | Authors: | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-08-21 | Release date: | 2022-08-31 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7V75
| Thermostabilized human prestin in complex with salicylate | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-HYDROXYBENZOIC ACID, CHOLESTEROL, ... | Authors: | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-08-21 | Release date: | 2022-08-31 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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8HIN
| Structure of human SGLT2-MAP17 complex with Phlorizin | Descriptor: | 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-11-21 | Release date: | 2023-11-22 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
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7E7Z
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7E87
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7E89
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7E83
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7E84
| CryoEM structure of human Kv4.2-KChIP1 complex | Descriptor: | Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 | Authors: | Kise, Y, Nureki, O. | Deposit date: | 2021-02-28 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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7E8E
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7E8G
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7E8B
| CryoEM structure of human Kv4.2-DPP6S complex | Descriptor: | Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 | Authors: | Kise, Y, Nureki, O. | Deposit date: | 2021-03-01 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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7E8H
| CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex | Descriptor: | Dipeptidyl aminopeptidase-like protein 6, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 | Authors: | Kise, Y, Nureki, O. | Deposit date: | 2021-03-01 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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1HLV
| CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA | Descriptor: | CENP-B BOX DNA, MAJOR CENTROMERE AUTOANTIGEN B | Authors: | Tanaka, Y, Nureki, O, Kurumizaka, H, Fukai, S, Kawaguchi, S, Ikuta, M, Iwahara, J, Okazaki, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2000-12-04 | Release date: | 2002-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA. EMBO J., 20, 2001
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1HZD
| CRYSTAL STRUCTURE OF HUMAN AUH PROTEIN, AN RNA-BINDING HOMOLOGUE OF ENOYL-COA HYDRATASE | Descriptor: | AU-BINDING PROTEIN/ENOYL-COA HYDRATASE | Authors: | Kurimoto, K, Fukai, S, Nureki, O, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-01-24 | Release date: | 2001-12-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase. Structure, 9, 2001
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1IU3
| CRYSTAL STRUCTURE OF THE E.COLI SEQA PROTEIN COMPLEXED WITH HEMIMETHYLATED DNA | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*TP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*AP*TP*CP*CP*TP*T)-3', SeqA protein | Authors: | Fujikawa, N, Kurumizaka, H, Nureki, O, Tanaka, Y, Yamazoe, M, Hiraga, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-02-26 | Release date: | 2003-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein. Nucleic Acids Res., 32, 2004
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1IVO
| Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal Growth Factor Receptor, ... | Authors: | Ogiso, H, Ishitani, R, Nureki, O, Fukai, S, Yamanaka, M, Kim, J.H, Saito, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-28 | Release date: | 2002-10-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains. Cell(Cambridge,Mass.), 110, 2002
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1IYW
| Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase | Descriptor: | Valyl-tRNA Synthetase | Authors: | Fukai, S, Nureki, O, Sekine, S, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-09-10 | Release date: | 2003-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase RNA, 9, 2003
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1IT7
| Crystal structure of archaeosine tRNA-guanine transglycosylase complexed with guanine | Descriptor: | Archaeosine tRNA-guanine transglycosylase, GUANINE, MAGNESIUM ION, ... | Authors: | Ishitani, R, Nureki, O, Fukai, S, Kijimoto, T, Nameki, N, Watanabe, M, Kondo, H, Sekine, M, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-01-11 | Release date: | 2002-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of archaeosine tRNA-guanine transglycosylase. J.Mol.Biol., 318, 2002
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1IT8
| Crystal structure of archaeosine tRNA-guanine transglycosylase from Pyrococcus horikoshii complexed with archaeosine precursor, preQ0 | Descriptor: | 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, MAGNESIUM ION, ZINC ION, ... | Authors: | Ishitani, R, Nureki, O, Fukai, S, Kijimoto, T, Nameki, N, Watanabe, M, Kondo, H, Sekine, M, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-01-11 | Release date: | 2002-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of archaeosine tRNA-guanine transglycosylase. J.Mol.Biol., 318, 2002
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1IUG
| The crystal structure of aspartate aminotransferase which belongs to subgroup IV from Thermus thermophilus | Descriptor: | PHOSPHATE ION, putative aspartate aminotransferase | Authors: | Katsura, Y, Shirouzu, M, Yamaguchi, H, Ishitani, R, Nureki, O, Kuramitsu, S, Hayashi, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-04 | Release date: | 2003-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV. Proteins, 55, 2004
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