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7AXZ
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BU of 7axz by Molmil
Ku70/80 complex apo form
Descriptor: X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
Authors:Hnizda, A, Tesina, P, Novak, P, Blundell, T.L.
Deposit date:2020-11-10
Release date:2021-02-10
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SAP domain forms a flexible part of DNA aperture in Ku70/80.
Febs J., 288, 2021
2G98
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BU of 2g98 by Molmil
human gamma-D-crystallin
Descriptor: Gamma crystallin D
Authors:Kmoch, S, Brynda, J, Awsav, B, Bezouska, K, Novak, P, Rezacova, P.
Deposit date:2006-03-06
Release date:2006-05-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Hum.Mol.Genet., 12, 2000
2JNT
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BU of 2jnt by Molmil
Structure of Bombyx mori Chemosensory Protein 1 in Solution
Descriptor: Chemosensory protein CSP1
Authors:Jansen, S, Zidek, L, Chmelik, J, Novak, P, Padrta, P, Picimbon, J, Lofstedt, C, Sklenar, V.
Deposit date:2007-02-02
Release date:2007-11-20
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Structure of Bombyx mori chemosensory protein 1 in solution
Arch.Insect Biochem.Physiol., 66, 2007
2M94
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BU of 2m94 by Molmil
NMR structure of the lymphocyte receptor NKR-P1A
Descriptor: Killer cell lectin-like receptor subfamily B member 1A
Authors:Chmelik, J, Rozbesky, D, Pospisilova, E, Novak, P.
Deposit date:2013-05-31
Release date:2014-06-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of the lymphocyte receptor NKR-P1A reveals a different conformation of the conserved loop compared to crystal structure
To be Published
2NAN
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BU of 2nan by Molmil
NMR structure of human DCL-1 (CD302) extracellular domain
Descriptor: CD302 antigen
Authors:Pospisilova, E, Kukacka, Z, Kavan, D, Novak, P, Chmelik, J.
Deposit date:2016-01-06
Release date:2017-01-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of human DCL-1 (CD302) extracellular domain
To be Published
2MTI
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BU of 2mti by Molmil
NMR structure of the lymphocyte receptor NKR-P1A
Descriptor: Killer cell lectin-like receptor subfamily B member 1A
Authors:Chmelik, J, Rozbesky, D, Pospisilova, E, Adamek, D, Novak, P.
Deposit date:2014-08-19
Release date:2015-11-11
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of the lymphocyte receptor Nkrp1a reveals a distinct conformation of the long loop region as compared to in the crystal structure.
Proteins, 84, 2016
5YI9
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BU of 5yi9 by Molmil
Solution structure of the LEDGF/p75 IBD - JPO2 (aa 56-91) complex
Descriptor: PC4 and SFRS1-interacting protein,Cell division cycle-associated 7-like protein
Authors:Veverka, V.
Deposit date:2017-10-03
Release date:2018-08-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6TRJ
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BU of 6trj by Molmil
LEDGF/p75 IBD dimer
Descriptor: PC4 and SFRS1-interacting protein
Authors:Kugler, M, Brynda, J.
Deposit date:2019-12-19
Release date:2020-09-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Fine-tuning of the LEDGF/p75 interaction network by dimerization
Structure
6TVM
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BU of 6tvm by Molmil
LEDGF/p75 dimer (residues 345-467)
Descriptor: PC4 and SFRS1-interacting protein
Authors:Lux, V, Veverka, V.
Deposit date:2020-01-10
Release date:2020-09-09
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular Mechanism of LEDGF/p75 Dimerization.
Structure, 28, 2020
3ZHO
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BU of 3zho by Molmil
X-ray structure of E.coli Wrba in complex with FMN at 1.2 A resolution
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVOPROTEIN WRBA
Authors:Kishko, I, Lapkouski, M, Brynda, J, Kuty, M, Carey, J, Smatanova, I.K, Ettrich, R.
Deposit date:2012-12-23
Release date:2013-08-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:1.2 A Resolution Crystal Structure of Escherichia Coli Wrba Holoprotein
Acta Crystallogr.,Sect.D, 69, 2013
5OPM
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BU of 5opm by Molmil
Crystal structure of D52N/R238W cN-II mutant bound to dATP and free phosphate
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPL
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BU of 5opl by Molmil
Crystal structure of K25E cN-II mutant
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
Authors:Kugler, M, Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPK
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BU of 5opk by Molmil
Crystal structure of D52N/R367Q cN-II mutant bound to dATP and free phosphate
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPP
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BU of 5opp by Molmil
Crystal structure of S408R cN-II mutant
Descriptor: BROMIDE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPN
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BU of 5opn by Molmil
Crystal structure of R39Q cN-II mutant
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPO
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BU of 5opo by Molmil
Crystal structure of R238G cN-II mutant
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5EDF
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BU of 5edf by Molmil
Crystal structure of the selenomethionine-substituted iron-regulated protein FrpD from Neisseria meningitidis
Descriptor: AZIDE ION, FrpC operon protein, HEXAETHYLENE GLYCOL, ...
Authors:Sviridova, E, Bumba, L, Rezacova, P, Sebo, P, Kuta Smatanova, I.
Deposit date:2015-10-21
Release date:2017-02-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.
Sci Rep, 7, 2017
5EDJ
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BU of 5edj by Molmil
Crystal structure of the Neisseria meningitidis iron-regulated outer membrane lipoprotein FrpD
Descriptor: FrpC operon protein
Authors:Sviridova, E, Bumba, L, Rezacova, P, Sebo, P, Kuta Smatanova, I.
Deposit date:2015-10-21
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.
Sci Rep, 7, 2017
8R6T
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BU of 8r6t by Molmil
NMR solution structure of thyropin IrThy-Cd from the hard tick Ixodes ricinus
Descriptor: Putative two thyropin protein (Fragment)
Authors:Srb, P, Veverka, V, Matouskova, Z, Orsaghova, K, Mares, M.
Deposit date:2023-11-23
Release date:2024-02-28
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.
Int J Mol Sci, 25, 2024
8R7I
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BU of 8r7i by Molmil
X-ray structure of blue laccase BP76 from the termite Neocapritermes taracua
Descriptor: 1,4-benzoquinone, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-3-O-sulfo-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Skerlova, J, Brynda, J, Rezacova, P.
Deposit date:2023-11-24
Release date:2024-08-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon.
Structure, 32, 2024
3M9Z
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BU of 3m9z by Molmil
Crystal Structure of extracellular domain of mouse NKR-P1A
Descriptor: Killer cell lectin-like receptor subfamily B member 1A, PHOSPHATE ION
Authors:Kolenko, P, Rozbesky, D, Bezouska, K, Hasek, J, Dohnalek, J.
Deposit date:2010-03-23
Release date:2011-04-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular architecture of mouse activating NKR-P1 receptors.
J.Struct.Biol., 175, 2011
5K7Y
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BU of 5k7y by Molmil
Crystal structure of enzyme in purine metabolism
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Skerlova, J, Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2016-05-27
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
3CCK
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BU of 3cck by Molmil
Human CD69
Descriptor: CHLORIDE ION, Early activation antigen CD69
Authors:Brynda, J, Vanek, O, Rezacova, P.
Deposit date:2008-02-26
Release date:2008-11-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice
Febs J., 275, 2008
5L4Z
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BU of 5l4z by Molmil
Crystal structure of enzyme in purine metabolism
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2016-05-27
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
5L50
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BU of 5l50 by Molmil
Crystal structure of enzyme in purine metabolism
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2016-05-27
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016

 

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