6TVM

LEDGF/p75 dimer (residues 345-467)

Summary for 6TVM

• Entry DOI: 10.2210/pdb6tvm/pdb
• NMR Information: BMRB: 34475
• Descriptor: PC4 and SFRS1-interacting protein (1 entity in total)
• Functional Keywords: epigenetic reader, integrase-binding domain, domain-swapped dimer, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 29289.71

Authors

Lux, V.,Veverka, V. (deposition date: 2020-01-10, release date: 2020-09-09, Last modification date: 2023-06-14)

• Primary citation: Lux, V.,Brouns, T.,Cermakova, K.,Srb, P.,Fabry, M.,Madlikova, M.,Horejsi, M.,Kukacka, Z.,Novak, P.,Kugler, M.,Brynda, J.,DeRijck, J.,Christ, F.,Debyser, Z.,Veverka, V.; Molecular Mechanism of LEDGF/p75 Dimerization.; Structure, 28:1288-1299.e7, 2020; PubMed: 32946742; DOI: 10.1016/j.str.2020.08.012

Experimental method

SOLUTION NMR