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5FEH
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BU of 5feh by Molmil
Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody
分子名称: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ...
著者Murrell, S, Wilson, I.A.
登録日2015-12-17
公開日2017-08-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
4YAQ
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BU of 4yaq by Molmil
Crystal structure of a computationally optimized PG9 mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PG9_N100FY Fab heavy chain, ...
著者Murrell, S, Julien, J.P, Wilson, I.A.
登録日2015-02-17
公開日2015-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
8GBX
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BU of 8gbx by Molmil
Crystal structure of PC39-50I, an anti-HIV broadly neutralizing antibody
分子名称: PC39-50I Fab heavy chain, PC39-50I Fab light chain
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBY
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BU of 8gby by Molmil
Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody
分子名称: GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBW
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BU of 8gbw by Molmil
Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ...
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GC0
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BU of 8gc0 by Molmil
Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBV
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BU of 8gbv by Molmil
Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody
分子名称: 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ...
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GC1
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BU of 8gc1 by Molmil
Crystal structure of the unmutated common ancestor (UCA) of the PC39-1 anti-HIV broadly neutralizing antibody lineage
分子名称: PC39-1 UCA Fab heavy chain, PC39-1 UCA Fab light chain
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBZ
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BU of 8gbz by Molmil
Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody
分子名称: DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain
著者Murrell, S, Omorodion, O, Wilson, I.A.
登録日2023-02-28
公開日2023-06-07
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
6B3D
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BU of 6b3d by Molmil
Crystal structure of anti-HIV antibody PGT128 in complex with a bacterially derived synthetic mimetic of Man9.
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Murrell, S, Wilson, I.A.
登録日2017-09-21
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.271 Å)
主引用文献Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Nat Commun, 8, 2017
6CA7
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BU of 6ca7 by Molmil
Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
分子名称: PCT64_13C heavy chain, PCT64_13C light chain
著者Murrell, S, Wilson, I.A.
登録日2018-01-29
公開日2018-06-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.643 Å)
主引用文献Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA6
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BU of 6ca6 by Molmil
Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_35S heavy chain, ...
著者Murrell, S, Wilson, I.A.
登録日2018-01-29
公開日2018-06-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6DCQ
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BU of 6dcq by Molmil
Ectodomain of full length, wild type HIV-1 glycoprotein clone PC64M18C043 in complex with PGT151 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rantalainen, K.
登録日2018-05-08
公開日2018-06-27
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA9
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BU of 6ca9 by Molmil
Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_LMCA Fab heavy chain, ...
著者Omorodion, O, Wilson, I.A.
登録日2018-01-29
公開日2018-06-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018

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件を2024-05-01に公開中

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