8T4Y
 
 | | Human HCN1 F186C S264C C309A bound to cAMP, reconstituted in LMNG + SPL | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | | Deposit date: | 2023-06-12 | | Release date: | 2024-06-19 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel.
Nat Commun, 15, 2024
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8T4M
 | | Closed human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | | Deposit date: | 2023-06-09 | | Release date: | 2024-06-12 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel.
Nat Commun, 15, 2024
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8T50
 | | Open human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | | Deposit date: | 2023-06-12 | | Release date: | 2024-07-03 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel.
Nat Commun, 15, 2024
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7UX1
 | | EcMscK in an Open Conformation | | Descriptor: | Mechanosensitive channel MscK | | Authors: | Mount, J.W, Yuan, P. | | Deposit date: | 2022-05-04 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.
Nat Commun, 13, 2022
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7UW5
 | | EcMscK G924S mutant in a closed conformation | | Descriptor: | Mechanosensitive channel MscK | | Authors: | Mount, J.W, Yuan, P. | | Deposit date: | 2022-05-02 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.
Nat Commun, 13, 2022
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8TS2
 | | Cryo-EM structure of human MRS2 with EDTA | | Descriptor: | Magnesium transporter MRS2 homolog, mitochondrial, Soluble cytochrome b562 fusion protein | | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | | Deposit date: | 2023-08-10 | | Release date: | 2024-08-14 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structure and function of the human mitochondrial MRS2 channel.
Nat.Struct.Mol.Biol., 32, 2025
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8TS3
 | | Cryo-EM structure of human MRS2 with Ca2+ | | Descriptor: | CALCIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | | Deposit date: | 2023-08-10 | | Release date: | 2024-08-14 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Structure and function of the human mitochondrial MRS2 channel.
Nat.Struct.Mol.Biol., 32, 2025
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8TS1
 | | Cryo-EM structure of human MRS2 with Mg2+ | | Descriptor: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | | Deposit date: | 2023-08-10 | | Release date: | 2024-08-14 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Structure and function of the human mitochondrial MRS2 channel.
Nat.Struct.Mol.Biol., 32, 2025
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