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6G16
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BU of 6g16 by Molmil
Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
Descriptor: Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
Deposit date:2018-03-20
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
5FXY
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BU of 5fxy by Molmil
Structure of the human RBBP4:MTA1(464-546) complex
Descriptor: HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1
Authors:Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R.
Deposit date:2016-03-03
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
4BKX
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BU of 4bkx by Molmil
The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex
Descriptor: ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ...
Authors:Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R.
Deposit date:2013-04-30
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
7AOA
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BU of 7aoa by Molmil
Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex
Descriptor: Histone deacetylase 1, Histone-binding protein RBBP4, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-10-14
Release date:2020-11-11
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (19.4 Å)
Cite:The topology of chromatin-binding domains in the NuRD deacetylase complex.
Nucleic Acids Res., 48, 2020
7AO8
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BU of 7ao8 by Molmil
Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex
Descriptor: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ...
Authors:Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-10-14
Release date:2020-11-11
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The topology of chromatin-binding domains in the NuRD deacetylase complex.
Nucleic Acids Res., 48, 2020
7AO9
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BU of 7ao9 by Molmil
Structure of the core MTA1/HDAC1/MBD2 NURD deacetylase complex
Descriptor: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ...
Authors:Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-10-14
Release date:2020-11-11
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:The topology of chromatin-binding domains in the NuRD deacetylase complex.
Nucleic Acids Res., 48, 2020
2MPM
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BU of 2mpm by Molmil
Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1
Descriptor: CCR3, Eotaxin
Authors:Millard, C.J, Ludeman, J.P, Canals, M, Bridgford, J.L, Hinds, M.G, Clayton, D.J, Christopoulos, A, Payne, R.J, Stone, M.J.
Deposit date:2014-05-26
Release date:2014-12-10
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1.
Structure, 22, 2014
5ICN
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BU of 5icn by Molmil
HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4
Descriptor: GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
6Z2J
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BU of 6z2j by Molmil
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-05-16
Release date:2020-07-08
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
6Z2K
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BU of 6z2k by Molmil
The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-05-16
Release date:2020-07-08
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Nat Commun, 11, 2020
2YHN
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BU of 2yhn by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
Authors:Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
2YHO
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BU of 2yho by Molmil
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Descriptor: ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ...
Authors:Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
3EJH
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BU of 3ejh by Molmil
Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen type-I a1 chain, Fibronectin, ...
Authors:Erat, M.C, Lowe, E.D, Campbell, I.D, Vakonakis, I.
Deposit date:2008-09-18
Release date:2009-02-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and structural analysis of type I collagen sites in complex with fibronectin fragments.
Proc.Natl.Acad.Sci.USA, 106, 2009
4D6K
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BU of 4d6k by Molmil
Structure of DNTTIP1 dimerisation domain.
Descriptor: DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1
Authors:Itoh, T, Fairall, L, Schwabe, J.W.R.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting.
Nucleic Acids Res., 43, 2015
2MWI
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BU of 2mwi by Molmil
The structure of the carboxy-terminal domain of DNTTIP1
Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1
Authors:Schwabe, J.W.R, Muskett, F.W, Itoh, T.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015

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