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8HPE
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BU of 8hpe by Molmil
Crystal structure of Leucine dehydrogenase
Descriptor: GLYCEROL, Leucine dehydrogenase, SULFATE ION
Authors:Li, X, Song, W.
Deposit date:2022-12-12
Release date:2024-03-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.
Chembiochem, 24, 2023
8HR6
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BU of 8hr6 by Molmil
leucine DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ from Bacillus thuringiensis
Descriptor: Leucine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Li, X, Song, W.
Deposit date:2022-12-14
Release date:2024-03-20
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.
Chembiochem, 24, 2023
2HBB
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BU of 2hbb by Molmil
Crystal Structure of the N-terminal Domain of Ribosomal Protein L9 (NTL9)
Descriptor: 50S ribosomal protein L9, ZINC ION
Authors:Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P.
Deposit date:2006-06-14
Release date:2007-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Energetically significant networks of coupled interactions within an unfolded protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
2HBA
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BU of 2hba by Molmil
Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9) K12M
Descriptor: 50S ribosomal protein L9, CHLORIDE ION, IMIDAZOLE, ...
Authors:Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P.
Deposit date:2006-06-14
Release date:2007-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Energetically significant networks of coupled interactions within an unfolded protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
6JM5
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BU of 6jm5 by Molmil
Crystal structure of TBC1D23 C terminal domain
Descriptor: SODIUM ION, TBC1 domain family member 23
Authors:Sun, Q, Huang, W.
Deposit date:2019-03-07
Release date:2019-10-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JL7
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BU of 6jl7 by Molmil
crystal structure of TBC1D23 N terminal domain
Descriptor: TBC1 domain family member 23
Authors:Sun, Q, Hu, W, Jia, D.
Deposit date:2019-03-04
Release date:2020-03-04
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain.
Plos Biol., 18, 2020
3EA5
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BU of 3ea5 by Molmil
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
Authors:Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
Deposit date:2008-08-24
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
2Q2B
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BU of 2q2b by Molmil
Crystal structure of the C-terminal domain of mouse acyl-CoA thioesterase 7
Descriptor: Cytosolic acyl coenzyme A thioester hydrolase
Authors:Guncar, G, Forwood, J.K, Kobe, B.
Deposit date:2007-05-27
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3MQ0
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BU of 3mq0 by Molmil
Crystal Structure of Agobacterium tumefaciens repressor BlcR
Descriptor: Transcriptional repressor of the blcABC operon
Authors:Chen, L.
Deposit date:2010-04-27
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:The Agrobacterium tumefaciens Transcription Factor BlcR Is Regulated via Oligomerization.
J.Biol.Chem., 286, 2011
1L0Q
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BU of 1l0q by Molmil
Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein
Descriptor: Surface layer protein
Authors:Jing, H, Takagi, J, Liu, J.-H, Lindgren, S, Zhang, R.-G, Joachimiak, A, Wang, J.-H, Springer, T.A.
Deposit date:2002-02-12
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Archaeal Surface Layer Proteins Contain beta Propeller, PKD, and beta Helix Domains and Are Related to Metazoan Cell Surface Proteins.
Structure, 10, 2002
4KN0
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BU of 4kn0 by Molmil
Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Folate receptor beta, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KM7
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BU of 4km7 by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, triclinic form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Folate receptor alpha, POTASSIUM ION
Authors:Kovach, A.R, Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KM6
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BU of 4km6 by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Folate receptor alpha
Authors:Singh, M, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KN1
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BU of 4kn1 by Molmil
Human folate receptor beta (FOLR2) in complex with the antifolate aminopterin
Descriptor: Aminopterin, CHLORIDE ION, Folate receptor beta, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
5EJN
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BU of 5ejn by Molmil
Crystal structure of Juno, the mammalian egg receptor for sperm Izumo1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sperm-egg fusion protein Juno
Authors:Nishimura, K, Han, L, Jovine, L.
Deposit date:2015-11-02
Release date:2016-02-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes.
Curr.Biol., 26, 2016
4KMX
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BU of 4kmx by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, hexagonal form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMY
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BU of 4kmy by Molmil
Human folate receptor beta (FOLR2) at neutral pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Folate receptor beta, POTASSIUM ION
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KN2
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BU of 4kn2 by Molmil
Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, CHLORIDE ION, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMZ
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BU of 4kmz by Molmil
Human folate receptor beta (FOLR2) in complex with the folate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FOLIC ACID, ...
Authors:Wibowo, A.S, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NXL
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BU of 4nxl by Molmil
Dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Descriptor: DszC
Authors:Zhang, L, Duan, X, Li, X, Rao, Z.
Deposit date:2013-12-09
Release date:2014-07-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the stabilization of active, tetrameric DszC by its C-terminus.
Proteins, 82, 2014
7T79
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BU of 7t79 by Molmil
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND AKA DIETHYL {[3-(3-{[5-(AZETIDINE-1-CARBON YL)PYRAZIN-2-YL]OXY}-5-(PROPAN-2-YLOXY)BENZAMIDO)-1H- PYRAZOL-1-YL]METHYL}PHOSPHONATE
Descriptor: Isoform 2 of Hexokinase-4, alpha-D-glucopyranose, diethyl {[3-(3-{[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy}-5-[(propan-2-yl)oxy]benzamido)-1H-pyrazol-1-yl]methyl}phosphonate
Authors:Muckelbauer, J.K.
Deposit date:2021-12-14
Release date:2022-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132).
J.Med.Chem., 65, 2022
7T78
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BU of 7t78 by Molmil
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND DIETHYL ({2-[3-(4-METHANESULFONYLPHENO XY)-5-{[(2S)-1-METHOXYPROPAN-2-YL]OXY}BENZAMIDO]-1,3-THIAZ OL-4-YL}METHYL)PHOSPHONATE
Descriptor: 1,2-ETHANEDIOL, Isoform 2 of Hexokinase-4, SODIUM ION, ...
Authors:Muckelbauer, J.K.
Deposit date:2021-12-14
Release date:2022-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132).
J.Med.Chem., 65, 2022
8XJ4
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BU of 8xj4 by Molmil
Structure of prostatic acid phosphatase in human semen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostatic acid phosphatase, alpha-D-mannopyranose, ...
Authors:Liu, X.Z, Li, J.L, Deng, D, Wang, X.
Deposit date:2023-12-20
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Purification, identification and Cryo-EM structure of prostatic acid phosphatase in human semen
Biochem.Biophys.Res.Commun., 702, 2024
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