4KMX

Human folate receptor alpha (FOLR1) at acidic pH, hexagonal form

Summary for 4KMX

Entry DOI	10.2210/pdb4kmx/pdb
Related	4KM6 4KM7 4KMY 4KMZ 4KN0 4KN1 4KN2
Descriptor	Folate receptor alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, ... (6 entities in total)
Functional Keywords	folate receptor alpha, folr1, folate receptor, folic acid, folates, 5-methyltetrahydrofolate, antifolates, folate-conjugates, gpi-anchored protein on eukaryotic membrane, transport protein, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	25214.74
Authors	Wibowo, A.S.,Dann III, C.E. (deposition date: 2013-05-08, release date: 2013-08-07, Last modification date: 2020-07-29)
Primary citation	Wibowo, A.S.,Singh, M.,Reeder, K.M.,Carter, J.J.,Kovach, A.R.,Meng, W.,Ratnam, M.,Zhang, F.,Dann, C.E. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110:15180-15188, 2013 Cited by PubMed: 23934049 DOI: 10.1073/pnas.1308827110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation