4KM7

Human folate receptor alpha (FOLR1) at acidic pH, triclinic form

Summary for 4KM7

• Entry DOI: 10.2210/pdb4km7/pdb
• Related: 4KM6 4KMX 4KMY 4KMZ 4KN0 4KN1 4KN2
• Descriptor: Folate receptor alpha, POTASSIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: folate receptor alpha, folr1, folate receptor, folic acid, folates, 5-methyltetrahydrofolate, antifolates, folate-conjugates, gpi-anchored protein on eukaryotic membrane, transport protein, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 49659.90

Authors

Kovach, A.R.,Wibowo, A.S.,Dann III, C.E. (deposition date: 2013-05-08, release date: 2013-08-07, Last modification date: 2020-07-29)

• Primary citation: Wibowo, A.S.,Singh, M.,Reeder, K.M.,Carter, J.J.,Kovach, A.R.,Meng, W.,Ratnam, M.,Zhang, F.,Dann, C.E.; Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.; Proc.Natl.Acad.Sci.USA, 110:15180-15188, 2013; PubMed: 23934049; DOI: 10.1073/pnas.1308827110

Experimental method

X-RAY DIFFRACTION (1.801 Å)